ID S9X9D5_CAMFR Unreviewed; 1354 AA.
AC S9X9D5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 13 {ECO:0000313|EMBL:EPY87002.1};
GN ORFNames=CB1_000282007 {ECO:0000313|EMBL:EPY87002.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY87002.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EPY87002.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
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DR EMBL; KB016575; EPY87002.1; -; Genomic_DNA.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 3.40.1620.60; -; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 4.
DR InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR InterPro; IPR041645; ADAMTS_CR_2.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723:SF20; A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 13; 1.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR Pfam; PF17771; ADAMTS_CR_2; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 3.
DR Pfam; PF00090; TSP_1; 1.
DR PRINTS; PR01857; ADAMTSFAMILY.
DR SMART; SM00209; TSP1; 5.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 4.
DR PROSITE; PS50092; TSP1; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR613273-3};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000313|EMBL:EPY87002.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030684};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 288..334
FT /note="ADAMTS cysteine-rich"
FT /evidence="ECO:0000259|Pfam:PF17771"
FT DOMAIN 404..518
FT /note="ADAMTS/ADAMTS-like cysteine-rich"
FT /evidence="ECO:0000259|Pfam:PF19236"
FT DOMAIN 521..643
FT /note="ADAMTS/ADAMTS-like Spacer 1"
FT /evidence="ECO:0000259|Pfam:PF05986"
FT DISULFID 295..329
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 323..334
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 359..396
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 363..401
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 374..386
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
SQ SEQUENCE 1354 AA; 145806 MW; E6097BDF7A43ED93 CRC64;
MGLLAASFTS ERVVNASLRL LRGPPHPCFT GGRTLLPLGA AARLTYCSGR VMGSSTLDLE
RAQGQSMPGA GMAQRGPPAA GGAGAVCTRL LSPFQEGDIV VGGDRLYIQP LKRQHRELVP
PWGGAQPHLI HRSNPTVHPA LVVPGHPLAP RLWRRAAQSV LYLELLVAVG PDVHAVHGED
TERYVLTNLN MGSELLRDPS LGAQFQVHLV KMVILTQPED APNITANITA SLLSVCEWSR
TINPEDDTDP SHADLVLYIT RWPGSGLALQ HHPAVCSLFL RFDLELPDGN RQDMCQALSC
HTDPLDQSSC SRLLIPLLDG TECGVGKWCS KGHCRSLAEL APIGAVHGHW SSWGPASPCS
RSCGGGVATR RRQCDNPRPA FGGRACIGAD LQAEMCNTQA CETTQLEFMS EQCSQTDGKP
LYLSPGSPSF YRWGAAVQYS QGDALCRHMC RAVGESFIVR RGDSFLDGTR CVPSSPREDG
TLSLCVSGSC RTFGCDGRMD SGQVRDACQV CGGDSSTCSP QNGSFRAGRA REYVTFLTIT
PNLTSIHIIN QRPLFTHLAV RLRGRYIVAG NGSISPSTSY PSLLEDSRVQ HKVALTEDRL
PRLEEIHIRG PTWDDMEIQV YRRYGAEYGA LARPDVTFTY FQPKRRQAWA WAAVRGACSV
SCGAGLRWVT YSCRDQASGQ WVEAARWVAG DFGPCSASCG GGLQERVVRC VEAQGGLLRT
LPHSRCRALA QQPVAVETCN SQPCPTREVS DTCSSACGAD LAGQNATCVL GTDGAEELVT
AGACSTDEKL ATLEPCVQAA CPPGGGHLDT QAPGEEAASA EGRARLEAPA THVWTPLAGP
CSVSCGRGLR ELRFQCTDSA LRTAVGEELC GLSSKPGSRW EVCRAAPCPA WWHYELAACS
GEDEDEEVLL DTQCQGLPRP EPQEPCSPEP CPPRSAAPRW KVTTLGPCSA SCGLGTATRS
VACVQLDRGQ DTAVDVRACA GLVRPQTRIP CMTAACTYRW HVSAWLQCSV SCGEGIQRRH
DTCLGPRAQV PVPADFCQHL PKPVTKAQQS PVMFLPLFCL GTWLAAGGVG KGVFTWERQD
VLLVGVSRLA RFLTARKARG PALQGVPHPD ALLTCPPAPL PGACGRQHLE PTGTIDMRGP
AQADCAVAIG RPLDEVVTLR VLESSLNCSA GEMLLLWGRL TWRKMCRRLS GMTFSSKANT
LVVRQRLVRP GGGVLLRYSS QPALGTFHRE CDMQLFGPRG EIVSPSLSPG GRNVGGCRIF
INVAPRARIV IHALATDMGT GTGNQGTDAS YILIRDIHSL RTTTFRGQQT LYWESEGSQA
EMEFSQGFLE AHTSLRGHYW TLQTRAPYRG SALP
//
