ID S9XE19_CAMFR Unreviewed; 677 AA.
AC S9XE19;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Actin-binding LIM protein 2 isoform 3 {ECO:0000313|EMBL:EPY88682.1};
GN ORFNames=CB1_000159013 {ECO:0000313|EMBL:EPY88682.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY88682.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EPY88682.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KB016455; EPY88682.1; -; Genomic_DNA.
DR AlphaFoldDB; S9XE19; -.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR CDD; cd09327; LIM1_abLIM; 1.
DR CDD; cd09328; LIM2_abLIM; 1.
DR CDD; cd09329; LIM3_abLIM; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR InterPro; IPR032402; AbLIM_anchor.
DR InterPro; IPR003128; Villin_headpiece.
DR InterPro; IPR036886; Villin_headpiece_dom_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR PANTHER; PTHR24213:SF6; ACTIN-BINDING LIM PROTEIN 2; 1.
DR Pfam; PF16182; AbLIM_anchor; 2.
DR Pfam; PF00412; LIM; 4.
DR Pfam; PF02209; VHP; 1.
DR SMART; SM00132; LIM; 4.
DR SMART; SM00153; VHP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 5.
DR SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR PROSITE; PS51089; HP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000030684};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 56..115
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 116..175
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 260..319
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 609..677
FT /note="HP"
FT /evidence="ECO:0000259|PROSITE:PS51089"
FT REGION 450..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 677 AA; 74417 MW; FB3B30B7276B8CEE CRC64;
MPSGLSWREC GPESPHHCWF AHLCPARSMF NSLLFPAVSE PQAAHGPLEK PPSTAILCNT
CGNVCKGEVL RVQNKYFHLQ CFVCKACGCD LAEGGFFVRQ GEYICTRDYQ TLYGTRCFSC
DQFIEGEVVS ALGRTYHPDC FVCATCRLPF PPGDRVTFNG KECVCQKCSL PKSAGTSVHL
SQGLWTAGGK SPGACPLGES TLLTCSRQSG LDLPALLSQL RVAQAATEDL GQEGFLGEAP
WQASARRAWR VGAPASLMRH SCGGCGAEIK NGQSLVALDK HWHLGCFKCK TCGKQLNAEY
ISKDGLPYCE ADYHTKFGIR CDGCEKYITG HVLEAGEKHY HPLCALCVRC GRMFSEGEEM
YLQACEPEAT HVWLPGARVP RDWVQAPEEQ MQSQVCSQVY LGTTPSAFQA KLGDEILDYR
DLAALPKNKA IYNIDRPDMI SYSPYISHSV GDRQSYSEGD QDDRSYKQCR TSSPSSTGSV
SLGRYTPTSR SPQHYSRPAG TVSVGTSSCL SLSQHPSPTS VFRHHYIPYF RGPVAQSPIS
KLSGLMSVLS LVVHKAGGSK TLEGPSPAQA AGFPYSKSDP VPGHGKNGLD HRNANLAPCG
ADLDASWGTR EYKIYPYDAL IVTNRIRVKL PKDVDRTRLE RHLSPEEFQE VFGMSVEEFD
RLALWKRNDL KKKALLF
//
