ID S9XXF0_CAMFR Unreviewed; 1512 AA.
AC S9XXF0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Activating signal cointegrator 1 complex subunit 3 {ECO:0000256|ARBA:ARBA00014590};
GN ORFNames=CB1_000897006 {ECO:0000313|EMBL:EPY79746.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY79746.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EPY79746.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|ARBA:ARBA00008708}.
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DR EMBL; KB017141; EPY79746.1; -; Genomic_DNA.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:UniProt.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF6; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 2.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030684}.
FT DOMAIN 106..307
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 682..821
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 854..1049
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1512 AA; 172440 MW; 66CE529DF35E7486 CRC64;
MNARSVPVLS RQRDSDVEKI RYPHVYDSQA EAMKTSAFIA GAKMILPEGI QRENNKMYEE
VKIPYSEPMP VGFQEKPVYI QDLDEIGQLA FKGMRRLNRI QSIVFETAYN TNENMLICAP
TGAGKTNIAM LTVLHEIRQH FQQGVIKKNE FKIVYVAPMK ALAAEMTNYF SKRLEPLGIV
VKELTGDMQL SKNEILRTQM LVTTPEKWDV VTRKSVGDVA LSQIVKLLIL DEVHLLHEDR
GPVLESIVAR TLRQVMVFVH ARNATVRTAM SLIERAKNNG QISYFLPTQG PEYGHAEKQG
TQIYAAKRGS FVDLGILDVM QIFGRAGRPQ FDKFGEGIII TTHDKLSHYL TLLTQQNPIE
SQFLESLADN LNAEIALGTV TNVEEAVKWI SYTYLYVRMR ANPLVYGISH KAYQIDPTLA
KHREQLVIEV GRKLDKARMI RFEERTGYFS STDLGRTASH YYIKYSTIET FNELFDAHKT
ESDIFAIVSK AEEFDQIKVR EEEIEELDAL LNNFCELSAP GGVENSYGKI NILLQTYISR
GEMDSFSLIS DSAYVAQNAA RIVRALFEIA LRKRWPAMTY RLLNLSKVID KRLWGWASPL
RQFSVLPPHI LTRLEEKNLT VDKLKDMRKD EIGHILHHVN IGLKVKQCVH QIPSVTMEAS
IQPITRTVLR VTLSICPDFT WNDQAVYIAP LKALVRERMD DWKVRIEEKL GKKVIELTGD
VTPDMKSIAK ADLIVTTPEK WDGISRSWQN RNYVKQVTIL IIDEIHLLGE ERGPVLEVIV
SRTNFISSHT EKPVRVVGLS TALANARDLA DWLNIRQMGL FNFRPSVRPV PLEVHIQGFP
GQHYCPRMAS MNKPTFQAIR SHSPAKPVLI FVSSRRQTRL TALELIAFLA TEEDPKQWLN
MDEREMENII GTVRDSNLKL TLAFGIGMHH AGLHERDRKT VEELFVNCKV QVLIATSTLA
WGVNFPAHLV IIKGTEYYDG KTRRYVDFPI TDVLQMMGRA GRPQFDDQGK AVILVHDIKK
DFYKKFLYEP FPVESSLLGV LSDHLNAEIA GGTITSKQDA MDYITWTYFF RRLIMNPSYY
NLSDVSHDSV NKFLSSLVEK SLVELEHSYC IEIGEDNRSI EPLTYGRIAS YYYLKHQTVK
MFKERLKPEC GTEELLSILS DAEEYTDLPV RHNEDHMNSE LAKCLPFESN PHSFDSPHTK
AHLLLQAHLS RAMLPCPDYD TDTKTVLDQA LRVCQAMLDV AAHQGWLVTV LNITNLVQMV
IQGRWLKDSS LLTIPHIENH HLHIFRKWSS GIKGPHAGFR GFTECLPELI HACGGKDHIF
SSMIEKELPA PKLKQAWNFL SHLPVIDVGL SVKGWWDDSE EGHDELPITT VTSDKRSDNK
WVKLHADQEY VLQVSLQRVS TGFHKGKQDS HAVTPRFPKS KDEGWFLILG EVDKKELIAL
KRVGYVRNHH VVSISFYTPE VPGRYIYTLY FMSDCYLGLD QQYDIHLNVT PASVSAQADE
ELSNALTDLQ VK
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