ID S9ZUQ9_9RHOO Unreviewed; 426 AA.
AC S9ZUQ9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:EPZ17277.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:EPZ17277.1};
GN ORFNames=M622_00490 {ECO:0000313|EMBL:EPZ17277.1};
OS Thauera terpenica 58Eu.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Thauera.
OX NCBI_TaxID=1348657 {ECO:0000313|EMBL:EPZ17277.1, ECO:0000313|Proteomes:UP000015455};
RN [1] {ECO:0000313|EMBL:EPZ17277.1, ECO:0000313|Proteomes:UP000015455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=58Eu {ECO:0000313|EMBL:EPZ17277.1,
RC ECO:0000313|Proteomes:UP000015455};
RA Liu B., Frostegard A.H., Shapleigh J.P.;
RT "Draft genome sequence of Thauera terpenica.";
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPZ17277.1}.
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DR EMBL; ATJV01000001; EPZ17277.1; -; Genomic_DNA.
DR AlphaFoldDB; S9ZUQ9; -.
DR STRING; 1348657.M622_00490; -.
DR PATRIC; fig|1348657.5.peg.97; -.
DR eggNOG; COG0183; Bacteria.
DR Proteomes; UP000015455; Unassembled WGS sequence.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919:SF138; ACETYL-COA C-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:EPZ17277.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000015455};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:EPZ17277.1}.
FT DOMAIN 28..289
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 296..417
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 112
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 375
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 405
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 426 AA; 44205 MW; 7414AE7CC0523D09 CRC64;
MPRPSKRSKA EHNLKEWIQQ ENCMSDPVVI VSVARTPLGG FQGDLSSVSA PQLGAIAIKA
AVERAGLQPE QVQEVMMGCV LPAGLGQAPA RQAAIGAGLP LSVACSTVSK VCGSGMKAAM
LAHDLILAGS SEVVVAGGME SMSNAPYLLP KARGGYRLGH GQMMDHMFLD GLEDSYSKES
KGRLMGTFAE DCATSFNFTR EAQDEFAVAS TTRAQAAIKG GDFAWEVVPV TVSGRKGDVV
IDHDEQPLKA QIEKIGSLKP AFKKDGTVTP ANSSSISDGA AALVLMRKST AEKLGLKPLA
TIVGHANHAQ EPALFTTAPV GAMQKVLAKA GWSTDEVDLW EINEAFAVVT MAAMHEMKLP
HDKVNVNGGA CALGHPIGAS GARILVTLIG ALRKRGLKRG VASLCIGGGE ATAMAIEVEA
AVGCGG
//
