ID SAM12_MOUSE Reviewed; 161 AA.
AC Q0VE29;
DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 24-JAN-2024, entry version 99.
DE RecName: Full=Sterile alpha motif domain-containing protein 12;
DE Short=SAM domain-containing protein 12;
GN Name=Samd12;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; BC119385; AAI19386.1; -; mRNA.
DR EMBL; BC119383; AAI19384.1; -; mRNA.
DR CCDS; CCDS37072.1; -.
DR RefSeq; NP_796199.1; NM_177225.4.
DR AlphaFoldDB; Q0VE29; -.
DR SMR; Q0VE29; -.
DR STRING; 10090.ENSMUSP00000077741; -.
DR iPTMnet; Q0VE29; -.
DR PhosphoSitePlus; Q0VE29; -.
DR PaxDb; 10090-ENSMUSP00000077741; -.
DR ProteomicsDB; 256830; -.
DR Antibodypedia; 13629; 92 antibodies from 15 providers.
DR Ensembl; ENSMUST00000078673.14; ENSMUSP00000077741.7; ENSMUSG00000058656.14.
DR GeneID; 320679; -.
DR KEGG; mmu:320679; -.
DR UCSC; uc007vri.1; mouse.
DR AGR; MGI:2444518; -.
DR CTD; 401474; -.
DR MGI; MGI:2444518; Samd12.
DR VEuPathDB; HostDB:ENSMUSG00000058656; -.
DR eggNOG; ENOG502RXXU; Eukaryota.
DR GeneTree; ENSGT00390000008161; -.
DR HOGENOM; CLU_105476_0_0_1; -.
DR InParanoid; Q0VE29; -.
DR OMA; LCRISFI; -.
DR OrthoDB; 5471567at2759; -.
DR PhylomeDB; Q0VE29; -.
DR TreeFam; TF325918; -.
DR BioGRID-ORCS; 320679; 2 hits in 76 CRISPR screens.
DR ChiTaRS; Samd12; mouse.
DR PRO; PR:Q0VE29; -.
DR Proteomes; UP000000589; Chromosome 15.
DR RNAct; Q0VE29; Protein.
DR Bgee; ENSMUSG00000058656; Expressed in lumbar dorsal root ganglion and 137 other cell types or tissues.
DR ExpressionAtlas; Q0VE29; baseline and differential.
DR GO; GO:0009898; C:cytoplasmic side of plasma membrane; IBA:GO_Central.
DR GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IBA:GO_Central.
DR CDD; cd09510; SAM_aveugle-like; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR039144; Aveugle-like_SAM_dom.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR20843; STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10; 1.
DR PANTHER; PTHR20843:SF2; STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 12; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..161
FT /note="Sterile alpha motif domain-containing protein 12"
FT /id="PRO_0000279503"
FT DOMAIN 77..143
FT /note="SAM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00184"
FT REGION 44..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 161 AA; 18245 MW; BC3759A104C315D8 CRC64;
MAVEALHCGL NPRGIDHSAH ADGIKLQIEG EGVESQSIKN RTFQKVPDQK GTPKRLQGEA
ETAKSATVKL SKPVALWTQQ DVCKWLKKHC PNQYQLYSES FKQHDITGRA LLRLTDKKLE
RMGIAQENQR QHILQQVLQL KVREEVRNLQ LLTQASVECS P
//
