ID SC61G_CIOIN Reviewed; 68 AA.
AC Q8I7D9;
DT 28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE RecName: Full=Protein transport protein Sec61 subunit gamma;
GN Name=SEC61G;
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Ievolella C., Valle G.;
RT "Some full length of Ciona intestinalis.";
RL Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Necessary for protein translocation in the endoplasmic
CC reticulum and multi-pass membrane protein biogenesis.
CC {ECO:0000250|UniProtKB:P60059}.
CC -!- SUBUNIT: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and
CC SEC61-gamma (By similarity). Component of the ribosome-associated ER
CC translocon complex (By similarity). {ECO:0000250|UniProtKB:P60058,
CC ECO:0000250|UniProtKB:P60059}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000250|UniProtKB:P60058}; Single-pass membrane protein
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SecE/SEC61-gamma family. {ECO:0000305}.
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DR EMBL; AJ297727; CAC82549.1; -; mRNA.
DR RefSeq; NP_001027676.1; NM_001032504.1.
DR AlphaFoldDB; Q8I7D9; -.
DR SMR; Q8I7D9; -.
DR STRING; 7719.ENSCINP00000030766; -.
DR Ensembl; ENSCINT00000036066.1; ENSCINP00000030766.1; ENSCING00000024485.1.
DR Ensembl; ENSCINT00000036955.1; ENSCINP00000031557.1; ENSCING00000018828.1.
DR GeneID; 445686; -.
DR KEGG; cin:445686; -.
DR CTD; 23480; -.
DR eggNOG; KOG3498; Eukaryota.
DR GeneTree; ENSGT00390000001319; -.
DR HOGENOM; CLU_167752_1_1_1; -.
DR InParanoid; Q8I7D9; -.
DR OMA; RDGNQFL; -.
DR OrthoDB; 593171at2759; -.
DR TreeFam; TF300232; -.
DR Proteomes; UP000008144; Unplaced.
DR GO; GO:0071261; C:Ssh1 translocon complex; IBA:GO_Central.
DR GO; GO:0008320; F:protein transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0043022; F:ribosome binding; ISS:UniProtKB.
DR GO; GO:0031204; P:post-translational protein targeting to membrane, translocation; IBA:GO_Central.
DR Gene3D; 1.20.5.820; Preprotein translocase SecE subunit; 1.
DR HAMAP; MF_00422; SecE; 1.
DR InterPro; IPR023391; Prot_translocase_SecE_dom_sf.
DR InterPro; IPR008158; Translocase_Sec61-g.
DR InterPro; IPR001901; Translocase_SecE/Sec61-g.
DR NCBIfam; TIGR00327; secE_euk_arch; 1.
DR PANTHER; PTHR12309:SF5; PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA; 1.
DR PANTHER; PTHR12309; SEC61 GAMMA SUBUNIT; 1.
DR Pfam; PF00584; SecE; 1.
DR SUPFAM; SSF103456; Preprotein translocase SecE subunit; 1.
DR PROSITE; PS01067; SECE_SEC61G; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Membrane; Protein transport; Reference proteome;
KW Translocation; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..68
FT /note="Protein transport protein Sec61 subunit gamma"
FT /id="PRO_0000104201"
FT TOPO_DOM 1..32
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 33..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 62..68
FT /note="Extracellular"
FT /evidence="ECO:0000255"
SQ SEQUENCE 68 AA; 7635 MW; 5CF398832F48A376 CRC64;
MDQVMAWVEP GKQFAKDSIR LVKRCTKPDR KEFQKIAVAT AIGFAIMGFI GFFVKLIHIP
INNIIVGS
//
