ID SODF_RICPR Reviewed; 209 AA.
AC Q9ZD15;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 05-DEC-2018, entry version 101.
DE RecName: Full=Superoxide dismutase [Mn/Fe];
DE EC=1.15.1.1;
GN Name=sodB; OrderedLocusNames=RP535;
OS Rickettsia prowazekii (strain Madrid E).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX NCBI_TaxID=272947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Madrid E;
RX PubMed=9823893; DOI=10.1038/24094;
RA Andersson S.G.E., Zomorodipour A., Andersson J.O.,
RA Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K.,
RA Eriksson A.-S., Winkler H.H., Kurland C.G.;
RT "The genome sequence of Rickettsia prowazekii and the origin of
RT mitochondria.";
RL Nature 396:133-140(1998).
CC -!- FUNCTION: Destroys superoxide anion radicals which are normally
CC produced within the cells and which are toxic to biological
CC systems.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC ChEBI:CHEBI:18421; EC=1.15.1.1;
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033; Evidence={ECO:0000250};
CC Note=Binds 1 Mn(2+) or Fe(2+) ion per subunit. {ECO:0000250};
CC -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase
CC family. {ECO:0000305}.
DR EMBL; AJ235272; CAA14984.1; -; Genomic_DNA.
DR PIR; F71657; F71657.
DR RefSeq; NP_220908.1; NC_000963.1.
DR RefSeq; WP_004599063.1; NC_000963.1.
DR ProteinModelPortal; Q9ZD15; -.
DR SMR; Q9ZD15; -.
DR STRING; 272947.RP535; -.
DR PRIDE; Q9ZD15; -.
DR EnsemblBacteria; CAA14984; CAA14984; CAA14984.
DR GeneID; 883209; -.
DR KEGG; rpr:RP535; -.
DR PATRIC; fig|272947.5.peg.545; -.
DR eggNOG; ENOG4105CK4; Bacteria.
DR eggNOG; COG0605; LUCA.
DR HOGENOM; HOG000013584; -.
DR KO; K04564; -.
DR OMA; KWGSFDK; -.
DR BioCyc; RPRO272947:G1GT0-536-MONOMER; -.
DR Proteomes; UP000002480; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR Gene3D; 1.10.287.990; -; 1.
DR Gene3D; 2.40.500.20; -; 1.
DR InterPro; IPR001189; Mn/Fe_SOD.
DR InterPro; IPR019833; Mn/Fe_SOD_BS.
DR InterPro; IPR019832; Mn/Fe_SOD_C.
DR InterPro; IPR019831; Mn/Fe_SOD_N.
DR InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR InterPro; IPR036314; SOD_C_sf.
DR Pfam; PF02777; Sod_Fe_C; 1.
DR Pfam; PF00081; Sod_Fe_N; 1.
DR PIRSF; PIRSF000349; SODismutase; 1.
DR PRINTS; PR01703; MNSODISMTASE.
DR SUPFAM; SSF46609; SSF46609; 1.
DR SUPFAM; SSF54719; SSF54719; 1.
DR PROSITE; PS00088; SOD_MN; 1.
PE 3: Inferred from homology;
KW Complete proteome; Iron; Manganese; Metal-binding; Oxidoreductase;
KW Reference proteome.
FT CHAIN 1 209 Superoxide dismutase [Mn/Fe].
FT /FTId=PRO_0000159999.
FT METAL 38 38 Manganese or iron. {ECO:0000250}.
FT METAL 90 90 Manganese or iron. {ECO:0000250}.
FT METAL 172 172 Manganese or iron. {ECO:0000250}.
FT METAL 176 176 Manganese or iron. {ECO:0000250}.
SQ SEQUENCE 209 AA; 24739 MW; E2114DF22068901B CRC64;
MTYCSKANQP SYPFILPDLP YDKESFKPHF TRETFDYHHG KHHNSYVQNL NNLIKDREEL
QKKDLEEIIE WSSQNAEVAI LNNASQIWNH TFFWYSIKPH GGGKPSGKVF EQISKDFGSF
EQFCAQFKQE AVGQFGSGWT WVVYHDNKLQ IIKTSNAGTP IVNFMKPILA CDVWEHAYYI
DYRNKRSDYI DIFIRHMINW KFVEDNLIQ
//
