ID SPEM1_BOVIN Reviewed; 313 AA.
AC Q32LJ5;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 2.
DT 08-NOV-2023, entry version 66.
DE RecName: Full=Spermatid maturation protein 1;
GN Name=SPEM1;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for proper cytoplasm removal during spermatogenesis.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}. Cytoplasm {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAI09547.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; BC109546; AAI09547.1; ALT_INIT; mRNA.
DR RefSeq; NP_001073054.2; NM_001079586.2.
DR AlphaFoldDB; Q32LJ5; -.
DR STRING; 9913.ENSBTAP00000042433; -.
DR PaxDb; 9913-ENSBTAP00000042433; -.
DR GeneID; 511321; -.
DR KEGG; bta:511321; -.
DR CTD; 374768; -.
DR eggNOG; ENOG502ST8J; Eukaryota.
DR InParanoid; Q32LJ5; -.
DR OrthoDB; 4869285at2759; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030317; P:flagellated sperm motility; IBA:GO_Central.
DR GO; GO:0007291; P:sperm individualization; IBA:GO_Central.
DR InterPro; IPR031368; SPEM1_N.
DR PANTHER; PTHR34834; SPERMATID MATURATION PROTEIN 1; 1.
DR PANTHER; PTHR34834:SF1; SPERMATID MATURATION PROTEIN 1; 1.
DR Pfam; PF15670; Spem1; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Cytoplasm; Developmental protein; Differentiation; Membrane;
KW Reference proteome; Spermatogenesis; Transmembrane; Transmembrane helix.
FT CHAIN 1..313
FT /note="Spermatid maturation protein 1"
FT /id="PRO_0000307805"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 71..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 243..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 263..289
FT /evidence="ECO:0000255"
FT COMPBIAS 105..119
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 313 AA; 35332 MW; A2AD46B7BA94FF61 CRC64;
MAMAERPRPG WASYHNPNTN SCQDLGNSIL LLLGLIICIN IGINMVTLLW RRLRGFLHQV
FRVICEKEAS KLRSPGKQTQ PSKHSSPAVH LRCTMDAVKM TVTPPPTRRR HRRGSSSRRA
RRPVAWAPDT DDDDDEKPPH QHTAACSHNW DYPEDWEGLQ TAQRFWTPWA QDTLEPPTQT
IRFQQTIEGR PLKREMQSDL GLEAYVYPVN PPLPSPQILS HKNSGGGAGA GAQAEQEQCA
PAEPPILGPA NVPDIPRRRS SGRVTYDARD VRRRLRELTR EVEALSHCYP LASGSSTAEG
TRKDWVYRSM TER
//
