ID SPZ9_ORYSJ Reviewed; 439 AA.
AC Q2R8P2; A0A0N7KSM8; C7J877; Q0ITS4;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 20-MAY-2008, sequence version 2.
DT 24-JAN-2024, entry version 100.
DE RecName: Full=Probable non-inhibitory serpin-Z9;
DE AltName: Full=OrysaZ9;
GN OrderedLocusNames=Os11g0222200, LOC_Os11g11500;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RG The rice full-length cDNA consortium;
RT "Oryza sativa full length cDNA.";
RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18060440; DOI=10.1007/s10142-007-0059-2;
RA Roberts T.H., Hejgaard J.;
RT "Serpins in plants and green algae.";
RL Funct. Integr. Genomics 8:1-27(2008).
CC -!- DOMAIN: The reactive center loop (RCL) extends out from the body of the
CC protein and directs binding to the target protease. The protease
CC cleaves the serpin at the reactive site within the RCL, establishing a
CC covalent linkage between the carboxyl group of the serpin reactive site
CC and the serine hydroxyl of the protease. The resulting inactive serpin-
CC protease complex is highly stable (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the serpin family. {ECO:0000305}.
CC -!- CAUTION: According to PubMed:18060440, it is predicted to be a non-
CC inhibitory serpin due to Gln-387 and Ile-390 which differ from the
CC conserved residues in the reactive center loop (RCL) that is involved
CC after cleavage in covalent linking and inhibition of the target
CC proteinase. {ECO:0000305}.
CC -!- CAUTION: It is uncertain whether Met-1 or Met-46 is the initiator.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABA92113.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAH95162.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; DP000010; ABA92113.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP008217; BAH95162.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP014967; BAT13258.1; -; Genomic_DNA.
DR EMBL; AK287588; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015615814.1; XM_015760328.1.
DR AlphaFoldDB; Q2R8P2; -.
DR SMR; Q2R8P2; -.
DR STRING; 39947.Q2R8P2; -.
DR PaxDb; 39947-Q2R8P2; -.
DR EnsemblPlants; Os11t0222200-01; Os11t0222200-01; Os11g0222200.
DR GeneID; 9270376; -.
DR Gramene; Os11t0222200-01; Os11t0222200-01; Os11g0222200.
DR KEGG; osa:9270376; -.
DR eggNOG; KOG2392; Eukaryota.
DR HOGENOM; CLU_023330_4_0_1; -.
DR InParanoid; Q2R8P2; -.
DR OMA; IFAPLCT; -.
DR OrthoDB; 387691at2759; -.
DR Proteomes; UP000000763; Chromosome 11.
DR Proteomes; UP000059680; Chromosome 11.
DR Genevisible; Q2R8P2; OS.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd02043; serpinP_plants; 1.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461:SF189; NON-INHIBITORY SERPIN-Z9-RELATED; 1.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..439
FT /note="Probable non-inhibitory serpin-Z9"
FT /id="PRO_0000334561"
FT REGION 12..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..413
FT /note="RCL"
FT SITE 403..404
FT /note="Reactive bond"
FT /evidence="ECO:0000255"
SQ SEQUENCE 439 AA; 47751 MW; 1D21CCBBF1854134 CRC64;
MQVSSYLRRA LRRPPFPAGD ANHRRLSSAP APKPEAPAEA MPPPPMPTRP WGEALAAAQR
AFCLPLAGRV LAAAGTGNAA VSAPAVHVSL ALAAGGARGA TRRQVLQALG CGGGGRGGAA
DAANVASRVV KRVLRDRSTS GGPRLAFAGG VWADASRSLS PEFVGLAGNV YGSAAKKADF
KNKPEDAPDQ INSWVKDSTK GTVTTLLPAG TIDQNTGLVL GSALYFRGRW LDRDDLRRTT
EQKFYCLDGT SVEVPFVEYD RTRLFAVHDN FKVIKLPYKQ GKNERKFSMY IFLPDDHDGL
FELTQKIFSE PMFLEQHLPT EKCHVGISVP NFKISFQIDV KDFLKDMGLE LPFLREAEFS
DMIKEDDSSG PLFLSDVLHK AVLEVDQKGI EETSVSMGLG KPLPAQHFKA DHPFFFMIRE
EVSGTVIFMG HVLDPSSRT
//
