ID SSGB_FRACC Reviewed; 143 AA.
AC Q2JDA6;
DT 20-JAN-2016, integrated into UniProtKB/Swiss-Prot.
DT 07-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=Sporulation-specific cell division protein SsgB {ECO:0000303|PubMed:19567872};
DE AltName: Full=Sporulation of Streptomyces griseus-like protein B {ECO:0000303|PubMed:19567872};
DE AltName: Full=SsgA-like protein B {ECO:0000303|PubMed:19567872};
DE Short=SALP B {ECO:0000303|PubMed:19567872};
GN Name=ssgB {ECO:0000303|PubMed:19567872};
GN OrderedLocusNames=Francci3_1359 {ECO:0000312|EMBL:ABD10736.1};
OS Frankia casuarinae (strain DSM 45818 / CECT 9043 / HFP020203 / CcI3).
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=106370 {ECO:0000312|EMBL:ABD10736.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC STRAIN=DSM 45818 / CECT 9043 / HFP020203 / CcI3
RC {ECO:0000303|PubMed:19567872};
RX PubMed=19567872; DOI=10.1074/jbc.m109.018564;
RA Xu Q., Traag B.A., Willemse J., McMullan D., Miller M.D., Elsliger M.A.,
RA Abdubek P., Astakhova T., Axelrod H.L., Bakolitsa C., Carlton D., Chen C.,
RA Chiu H.J., Chruszcz M., Clayton T., Das D., Deller M.C., Duan L.,
RA Ellrott K., Ernst D., Farr C.L., Feuerhelm J., Grant J.C., Grzechnik A.,
RA Grzechnik S.K., Han G.W., Jaroszewski L., Jin K.K., Klock H.E., Knuth M.W.,
RA Kozbial P., Krishna S.S., Kumar A., Marciano D., Minor W., Mommaas A.M.,
RA Morse A.T., Nigoghossian E., Nopakun A., Okach L., Oommachen S.,
RA Paulsen J., Puckett C., Reyes R., Rife C.L., Sefcovic N., Tien H.J.,
RA Trame C.B., van den Bedem H., Wang S., Weekes D., Hodgson K.O., Wooley J.,
RA Deacon A.M., Godzik A., Lesley S.A., Wilson I.A., van Wezel G.P.;
RT "Structural and functional characterizations of SsgB, a conserved activator
RT of developmental cell division in morphologically complex actinomycetes.";
RL J. Biol. Chem. 284:25268-25279(2009).
RN [2] {ECO:0000312|EMBL:ABD10736.1, ECO:0000312|Proteomes:UP000001937}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45818 / CECT 9043 / HFP020203 / CcI3
RC {ECO:0000312|EMBL:ABD10736.1, ECO:0000312|Proteomes:UP000001937};
RX PubMed=17151343; DOI=10.1101/gr.5798407;
RA Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A.,
RA Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P.,
RA Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C.,
RA Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J.,
RA Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F.,
RA Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C.,
RA Benson D.R.;
RT "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT reflect host range and host plant biogeography.";
RL Genome Res. 17:7-15(2007).
CC -!- FUNCTION: Involved in sporulation-specific cell division
CC (PubMed:19567872). Required for early stages of sporulation. Important
CC in the process of growth cessation prior to sporulation-specific cell
CC division. Recruits cell division protein FtsZ to the future septum
CC sites and tethers the contractile ring structure (Z ring) to the
CC cytoplasmic membrane during sporulation. Stimulates polymerization and
CC filament length of FtsZ in vitro (By similarity).
CC {ECO:0000250|UniProtKB:Q47N25, ECO:0000250|UniProtKB:Q9L268,
CC ECO:0000269|PubMed:19567872}.
CC -!- SUBUNIT: Interacts with SsgA. Interacts with FtsZ (via N-terminus).
CC {ECO:0000250|UniProtKB:Q47N25, ECO:0000250|UniProtKB:Q9L268}.
CC -!- SUBCELLULAR LOCATION: Cell septum {ECO:0000250|UniProtKB:Q9L268}.
CC Note=Localizes to the divisome in sporogenic aerial hyphae in a ladder-
CC like manner. Temporospatial localization is controlled by SsgA and it
CC colocalizes with SsgA in presporulation foci. Localizes to the septum
CC sites prior to FtsZ and after that colocalizes with FtsZ at the
CC divisome throughout cell division. {ECO:0000250|UniProtKB:Q9L268}.
CC -!- SIMILARITY: Belongs to the SsgA family. {ECO:0000305}.
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DR EMBL; CP000249; ABD10736.1; -; Genomic_DNA.
DR RefSeq; WP_009739629.1; NZ_JENI01000007.1.
DR AlphaFoldDB; Q2JDA6; -.
DR SMR; Q2JDA6; -.
DR STRING; 106370.Francci3_1359; -.
DR KEGG; fra:Francci3_1359; -.
DR eggNOG; ENOG5032RFA; Bacteria.
DR HOGENOM; CLU_126599_0_1_11; -.
DR OrthoDB; 3853096at2; -.
DR PhylomeDB; Q2JDA6; -.
DR Proteomes; UP000001937; Chromosome.
DR GO; GO:0030428; C:cell septum; ISS:UniProtKB.
DR GO; GO:1990586; C:divisome complex; ISS:UniProtKB.
DR GO; GO:0031160; C:spore wall; ISS:UniProtKB.
DR GO; GO:0043936; P:asexual sporulation resulting in formation of a cellular spore; IDA:UniProtKB.
DR GO; GO:0051301; P:cell division; IDA:UniProtKB.
DR GO; GO:0090529; P:cell septum assembly; ISS:UniProtKB.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0030448; P:hyphal growth; ISS:UniProtKB.
DR GO; GO:0051781; P:positive regulation of cell division; ISS:UniProtKB.
DR GO; GO:0042244; P:spore wall assembly; ISS:UniProtKB.
DR Gene3D; 2.30.31.20; Sporulation-specific cell division protein SsgB; 1.
DR InterPro; IPR006776; SsgB.
DR InterPro; IPR038658; SsgB_sf.
DR Pfam; PF04686; SsgA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Reference proteome; Septation; Sporulation.
FT CHAIN 1..143
FT /note="Sporulation-specific cell division protein SsgB"
FT /id="PRO_0000435309"
SQ SEQUENCE 143 AA; 15282 MW; 5FFDA20221DAA4BD CRC64;
MTIRHDSITA ELALRLVVPG GAPVPVAATV RYEPADPYAI SIGFRTGADE VVEWTFARQL
LSDGVRRPAG DGDVQVWPAA QSGGRIVCLS LSSPSGHALF EMPRSEVLAF LRRTYSAVPL
GGESDIIDLD AELALLIWGG PER
//
