ID SUT33_ARATH Reviewed; 631 AA.
AC Q9SXS2; O49307;
DT 26-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT 26-SEP-2003, sequence version 2.
DT 27-MAR-2024, entry version 137.
DE RecName: Full=Probable sulfate transporter 3.3;
DE AltName: Full=AST91;
GN Name=SULTR3;3; OrderedLocusNames=At1g23090; ORFNames=T26J12.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RA Takahashi H., Saito K.;
RT "Sulfate transporter AST91 from Arabidopsis thaliana.";
RL Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP TISSUE SPECIFICITY.
RA Takahashi H., Watanbe A., Sasakura N., Asanuma W., Nakamura M., Saito K.;
RT "Molecular characterization of the sulfate transporter gene family in
RT Arabidopsis thaliana.";
RL (In) Brunold C. (eds.);
RL Sulfur nutrition and sulfur assimilation in higher plants, pp.265-267, Paul
RL Haupt, Bern (2000).
CC -!- FUNCTION: H(+)/sulfate cotransporter that may play a role in the
CC regulation of sulfate assimilation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed only in leaves. {ECO:0000269|Ref.4}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB023423; BAA75015.1; -; mRNA.
DR EMBL; AC002311; AAC00610.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30335.1; -; Genomic_DNA.
DR PIR; B86365; B86365.
DR RefSeq; NP_173722.1; NM_102157.4.
DR AlphaFoldDB; Q9SXS2; -.
DR SMR; Q9SXS2; -.
DR BioGRID; 24156; 7.
DR IntAct; Q9SXS2; 7.
DR STRING; 3702.Q9SXS2; -.
DR iPTMnet; Q9SXS2; -.
DR PaxDb; 3702-AT1G23090-1; -.
DR ProteomicsDB; 226831; -.
DR EnsemblPlants; AT1G23090.1; AT1G23090.1; AT1G23090.
DR GeneID; 838917; -.
DR Gramene; AT1G23090.1; AT1G23090.1; AT1G23090.
DR KEGG; ath:AT1G23090; -.
DR Araport; AT1G23090; -.
DR TAIR; AT1G23090; SULTR3.
DR eggNOG; KOG0236; Eukaryota.
DR HOGENOM; CLU_003182_13_2_1; -.
DR InParanoid; Q9SXS2; -.
DR OMA; PALYWIP; -.
DR OrthoDB; 2880581at2759; -.
DR PhylomeDB; Q9SXS2; -.
DR PRO; PR:Q9SXS2; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SXS2; baseline and differential.
DR Genevisible; Q9SXS2; AT.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR018045; S04_transporter_CS.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00815; sulP; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR PANTHER; PTHR11814:SF93; SULFATE TRANSPORTER 3.3-RELATED; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS01130; SLC26A; 1.
DR PROSITE; PS50801; STAS; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Sulfate transport; Symport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..631
FT /note="Probable sulfate transporter 3.3"
FT /id="PRO_0000080179"
FT TOPO_DOM 1..69
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 91..92
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 114..117
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 139..144
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 166..171
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 193..223
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 245..256
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 278..309
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 310..330
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 331..347
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 348..368
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 369..384
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 385..405
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 406..410
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 411..431
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 432..441
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 442..462
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 463..631
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 497..621
FT /note="STAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00198"
FT CONFLICT 89..90
FT /note="KL -> NV (in Ref. 1; BAA75015)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 631 AA; 69070 MW; 21E48F67125E6200 CRC64;
MEVHKVVAPP HKSTVAKLKT KLKETFFPDD PLRQFRGQPN RTKLIRAAQY IFPILQWCPE
YSFSLLKSDV VSGLTIASLA IPQGISYAKL ANLPPIVGLY SSFVPPLVYA VLGSSRDLAV
GPVSIASLIL GSMLRQQVSP VDDPVLFLQL AFSSTFFAGL FQASLGILRL GFIIDFLSKA
TLIGFMGGAA IIVSLQQLKG LLGITHFTKH MSVVPVLSSV FQHTNEWSWQ TIVMGVCFLL
FLLSTRHLSM KKPKLFWVSA GAPLLSVIVS TLLVFVFRAE RHGISVIGKL PEGLNPPSWN
MLQFHGSHLA LVAKTGLVTG IVSLTEGIAV GRTFAALKNY HVDGNKEMIA IGLMNVVGSA
TSCYVTTGAF SRSAVNNNAG AKTAVSNIVM SVTVMVTLLF LMPLFEYTPN VVLGAIIVTA
VIGLIDLPAA CHIWKIDKFD FLVMLCAFFG VIFLSVQNGL AIAVGLSLFK ILMQVTRPKM
VIMGNIPGTD IYRDLHHYKE AQRIPGFLVL SIESPVNFAN SNYLTERTSR WIEECEEEEA
QEKHSSLQFL ILEMSAVSGV DTNGVSFFKE LKKTTAKKDI ELVFVNPLSE VVEKLQRADE
QKEFMRPEFL FLTVAEAVAS LSLKGPSLSN V
//
