ID T0G1Q1_9SPHN Unreviewed; 1136 AA.
AC T0G1Q1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE AltName: Full=DNA 3'-5' helicase II {ECO:0000256|ARBA:ARBA00034923};
GN ORFNames=L485_20290 {ECO:0000313|EMBL:EQA97605.1};
OS Sphingobium baderi LL03.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1114964 {ECO:0000313|EMBL:EQA97605.1, ECO:0000313|Proteomes:UP000015524};
RN [1] {ECO:0000313|EMBL:EQA97605.1, ECO:0000313|Proteomes:UP000015524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LL03 {ECO:0000313|EMBL:EQA97605.1,
RC ECO:0000313|Proteomes:UP000015524};
RX PubMed=24051322;
RA Kaur J., Verma H., Tripathi C., Khurana J.P., Lal R.;
RT "Draft Genome Sequence of a Hexachlorocyclohexane-Degrading Bacterium,
RT Sphingobium baderi Strain LL03T.";
RL Genome Announc. 1:e00751-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQA97605.1}.
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DR EMBL; ATIB01000086; EQA97605.1; -; Genomic_DNA.
DR RefSeq; WP_021246600.1; NZ_KQ130471.1.
DR AlphaFoldDB; T0G1Q1; -.
DR PATRIC; fig|1114964.3.peg.3986; -.
DR eggNOG; COG1074; Bacteria.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000015524; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR014151; DNA_helicase_AddA.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; TIGR02784; addA_alphas; 1.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000015524}.
FT DOMAIN 12..489
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 508..783
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT REGION 909..965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 918..935
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 33..40
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1136 AA; 123778 MW; A0FE04F230477103 CRC64;
MAATMARKAS PLQPLADKQA LAAAPDAHVW LSASAGTGKT HVLTARVFRL LLQGVRPENI
LCLTFTKAGA AEMADRIHDR LAAWVQMEEG DLFNDLEALG EEAGPEARDR ARRLFAEVLE
STGGGLRIQT IHGFCQQLLT SFPLEAGLTP GFRPLDQREQ SALARQVLAD LAVEADQNGD
TALTGALQAL SLRLGEAGAE QFLLRAAARL DALNRLPEAI GPWLKDELGL PAGDVDAWLA
GQCDDAVFDM RTLAAIAQSN ADWGSGRALE RCERIARWRA LTPDGRAAAL RDLHAAWAKA
DGGFVSAKGW VPPADGYLEM AARMHERCAD LLGVKLLADY ADLLARALHA GRAYARAYAG
AKAVAGAVDF DDLIARTAAL LQQDGIADWI RYKLDQRVDH VLVDEAQDTN VSQWQIIGAL
TAEFFAGEGA KGDKVRTIFT VGDFKQAIFG FQGTSPLAFA AAQRAFQGQA DNVAHPFHAL
SLDRSFRSTP AILDVVDRTI ATLRAQRLGL EDQDVRHVSA NPFPGEVLLW KPIVAGLNED
AEGEEDWAAD QERALAARIA RQIRQWLDDG LMLESKGRPV RPGDIMILVR RRSELARLIV
ARLYEEQVAV AGIDRLRLNA PLAVRDLLAA LRFAVQPEDE LNLAALLVSP LIGWSQDELM
TRLIGRDRAG GLWRHLTGSL DDDLVRPLRD LLAGADFTTP YRYLEAILSG PMDGRRRLIE
RLGPEAADPI EELLNAALAF ETDDYPSLQR FIDWFDRGEV EIVRDAAAQG DALRLLTVHG
AKGLQAPIVI LADACLDPDA GHRADTLEWN GLPILPPRKE ERKGPVGHVA EAAAAADREE
HWRLLYVALT RAEERLVVAG SLGPRAKGEV KPESWFGAVE NALISLEAEW QADPLWGARR
SWRGAQILPP RPLQAAHPEE KASQDRPDWL DRPAPVEARP PRPLAPSASV EDDVPYPPPG
PAMRSAAERG RWLHALFERL PDIAPERRRE SAERWLEQQG AADMALRREV VDHALAVIEA
PGFSTLFGPG SLAEAPIAAV VGETVIAGTV DRLCVGEDLI QLVDFKTGRI APLSIEEVPA
AHVRQMAAYV SALRVIFPQR TIEAGLLYTS APRLISLPPE VLDANKPGFA TAQDNL
//
