ID T0GBA2_9SPHN Unreviewed; 401 AA.
AC T0GBA2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:EQB01066.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:EQB01066.1};
GN ORFNames=L485_11420 {ECO:0000313|EMBL:EQB01066.1};
OS Sphingobium baderi LL03.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1114964 {ECO:0000313|EMBL:EQB01066.1, ECO:0000313|Proteomes:UP000015524};
RN [1] {ECO:0000313|EMBL:EQB01066.1, ECO:0000313|Proteomes:UP000015524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LL03 {ECO:0000313|EMBL:EQB01066.1,
RC ECO:0000313|Proteomes:UP000015524};
RX PubMed=24051322;
RA Kaur J., Verma H., Tripathi C., Khurana J.P., Lal R.;
RT "Draft Genome Sequence of a Hexachlorocyclohexane-Degrading Bacterium,
RT Sphingobium baderi Strain LL03T.";
RL Genome Announc. 1:e00751-13(2013).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQB01066.1}.
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DR EMBL; ATIB01000062; EQB01066.1; -; Genomic_DNA.
DR RefSeq; WP_021245127.1; NZ_KQ130472.1.
DR AlphaFoldDB; T0GBA2; -.
DR PATRIC; fig|1114964.3.peg.2229; -.
DR eggNOG; COG0183; Bacteria.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000015524; Unassembled WGS sequence.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:EQB01066.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000015524};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:EQB01066.1}.
FT DOMAIN 5..228
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 279..400
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 91
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 357
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 387
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 401 AA; 41891 MW; 5F35EEF2391FCEA9 CRC64;
MAEAYIYDAV RTPRGRGRPD GALHEITALS LAVQTLQALR DRNSLDTAQV DDVILGCVMP
VGEQGSDIAR IAALVAGYSQ DVPGLQINRF CASGLEACNI AAAKVIAGEA RFAIGGGVES
MSRVPLAADG GAMLVDPSFA YDHYYAPQGI GADMIATMDG FTREDVDGYA VQSQRRAAKA
WEEGRFSKSV IPVLDQSGVV RLAHDEHMRP GTDVQSLGAL KPAFAKMGEA GYDAAAHARY
PGLGPINHVH HGGNSSGIVD GASTVLIGSK EAGDAAGLKP RARFRCGVSI GSEPTIMLTG
PEFVTRKALQ RVGMALSDID LFELNEAFAA VVLRYQHVLD IDPEKLNVNG GAIAMGHPLG
ATGAMILGTV LDELERTGKG TALVNLCVGA GMGTAAIIER V
//
