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Database: UniProt
Entry: T0GD41_9SPHN
LinkDB: T0GD41_9SPHN
Original site: T0GD41_9SPHN 
ID   T0GD41_9SPHN            Unreviewed;       240 AA.
AC   T0GD41;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   RecName: Full=Heme exporter protein C {ECO:0000256|ARBA:ARBA00016463, ECO:0000256|RuleBase:RU364092};
DE   AltName: Full=Cytochrome c-type biogenesis protein {ECO:0000256|RuleBase:RU364092};
GN   Name=ccmC {ECO:0000256|RuleBase:RU364092};
GN   ORFNames=L485_19605 {ECO:0000313|EMBL:EQA97952.1};
OS   Sphingobium baderi LL03.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=1114964 {ECO:0000313|EMBL:EQA97952.1, ECO:0000313|Proteomes:UP000015524};
RN   [1] {ECO:0000313|EMBL:EQA97952.1, ECO:0000313|Proteomes:UP000015524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LL03 {ECO:0000313|EMBL:EQA97952.1,
RC   ECO:0000313|Proteomes:UP000015524};
RX   PubMed=24051322;
RA   Kaur J., Verma H., Tripathi C., Khurana J.P., Lal R.;
RT   "Draft Genome Sequence of a Hexachlorocyclohexane-Degrading Bacterium,
RT   Sphingobium baderi Strain LL03T.";
RL   Genome Announc. 1:e00751-13(2013).
CC   -!- FUNCTION: Required for the export of heme to the periplasm for the
CC       biogenesis of c-type cytochromes. {ECO:0000256|ARBA:ARBA00002442,
CC       ECO:0000256|RuleBase:RU364092}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU364092}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CcmC/CycZ/HelC family.
CC       {ECO:0000256|ARBA:ARBA00005840, ECO:0000256|RuleBase:RU364092}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EQA97952.1}.
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DR   EMBL; ATIB01000085; EQA97952.1; -; Genomic_DNA.
DR   RefSeq; WP_021246465.1; NZ_KQ130471.1.
DR   AlphaFoldDB; T0GD41; -.
DR   PATRIC; fig|1114964.3.peg.3850; -.
DR   eggNOG; COG0755; Bacteria.
DR   OrthoDB; 9778550at2; -.
DR   Proteomes; UP000015524; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR003557; Cyt_c_biogenesis_CcmC.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   NCBIfam; TIGR01191; ccmC; 1.
DR   PANTHER; PTHR30071:SF17; CYTOCHROME C ASSEMBLY PROTEIN-RELATED; 1.
DR   PANTHER; PTHR30071; HEME EXPORTER PROTEIN C; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   PRINTS; PR01386; CCMCBIOGNSIS.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane {ECO:0000256|RuleBase:RU364092};
KW   Cell membrane {ECO:0000256|RuleBase:RU364092};
KW   Cytochrome c-type biogenesis {ECO:0000256|RuleBase:RU364092};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364092};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015524};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU364092};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU364092}; Transport {ECO:0000256|RuleBase:RU364092}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        59..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        92..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        123..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        153..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        198..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   DOMAIN          27..182
FT                   /note="Cytochrome c assembly protein"
FT                   /evidence="ECO:0000259|Pfam:PF01578"
SQ   SEQUENCE   240 AA;  26189 MW;  199FC34FF6197A21 CRC64;
     MHRFANPARF LKIARPLTGW LFWPGLSLIL AGCFCGLFVT PADYLQGETV RILYIHVPAA
     WLGMAGWSGI AVAALMQLVW RHPLASIAGR ALAAPGALFT AICLATGSIW GRPTWGTWWE
     WDGRMTSMLV LLFLYLGYIA LANASARQGQ GGVSAVTAIF GLVGAINIPI INRSVVWWNS
     LHQGPSITLR GSSIDGSLLW PLGLTFLGFS LLFGAIVLMR MRTLLARNKI EARMQRLARG
//
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