ID T0IEC2_9SPHN Unreviewed; 546 AA.
AC T0IEC2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Glucose-methanol-choline oxidoreductase {ECO:0000313|EMBL:EQB10040.1};
GN ORFNames=L284_17950 {ECO:0000313|EMBL:EQB10040.1};
OS Novosphingobium lindaniclasticum LE124.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1096930 {ECO:0000313|EMBL:EQB10040.1, ECO:0000313|Proteomes:UP000015527};
RN [1] {ECO:0000313|EMBL:EQB10040.1, ECO:0000313|Proteomes:UP000015527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LE124 {ECO:0000313|EMBL:EQB10040.1,
RC ECO:0000313|Proteomes:UP000015527};
RX PubMed=24029761;
RA Saxena A., Nayyar N., Sangwan N., Kumari R., Khurana J.P., Lal R.;
RT "Genome Sequence of Novosphingobium lindaniclasticum LE124T, Isolated from
RT a Hexachlorocyclohexane Dumpsite.";
RL Genome Announc. 1:e00715-13(2013).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQB10040.1}.
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DR EMBL; ATHL01000120; EQB10040.1; -; Genomic_DNA.
DR RefSeq; WP_021235353.1; NZ_ATHL01000120.1.
DR AlphaFoldDB; T0IEC2; -.
DR PATRIC; fig|1096930.3.peg.3551; -.
DR eggNOG; COG2303; Bacteria.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000015527; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU003968};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003968};
KW Reference proteome {ECO:0000313|Proteomes:UP000015527}.
FT DOMAIN 85..108
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT DOMAIN 258..272
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
SQ SEQUENCE 546 AA; 58292 MW; B2F843A3D52FD79F CRC64;
MAKAWDYIIV GAGSAGCVMA ERLSADGRSQ VLLLEAGGSN DSFWVTLPKG VAKLVKKPEH
MWAYPVSQPR EEGANESGGE VWIRGKGLGG SSSINGMIWS RGEPADYDAW ESEAGATGWN
GASMTEAFLE LEDHAAGASE LRGSGGLVHV DPACYTYPLA ERMIESGEAL GLRRVDDLNA
ATGPRVGYYS HNIRNGRRES SARTYLAAAR GRPNLTIVTG ALAERIVFDG TRVVGLEAAV
NGRPQRFDCA GEIVVSAGAM ESPLLLQRSG IGDSDRLRAA GIAPLVHSPD VGERMIEHLS
ISLPYRLEHG RGTNRSFFGI GAGLAMLRYL LRHDGVLATG PFEVGAFCNV AHPDGRTDAQ
FYLGGYTFKV GDDKDPVPLD KIDPLPGVTI YGQLLRLTSE SAVRATGPNP GDPLDIRHNF
LTTEHDRRSA IALVRKMRAF IAAAPLGRMV GPELVPGAQV ESDEDVLAAF RRLSSCGLHA
IRSCRMGDDP EAVVDARLRV KGVQGLRVAD CSVMPGHVTG NTNAPAMALG LRGAKLMRED
RSPHPS
//
