ID T0IWD4_9SPHN Unreviewed; 231 AA.
AC T0IWD4;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=M529_21725 {ECO:0000313|EMBL:EQB30076.1};
OS Sphingobium ummariense RL-3.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1346791 {ECO:0000313|EMBL:EQB30076.1, ECO:0000313|Proteomes:UP000015523};
RN [1] {ECO:0000313|EMBL:EQB30076.1, ECO:0000313|Proteomes:UP000015523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RL-3 {ECO:0000313|EMBL:EQB30076.1,
RC ECO:0000313|Proteomes:UP000015523};
RX PubMed=24233594;
RA Kohli P., Dua A., Sangwan N., Oldach P., Khurana J.P., Lal R.;
RT "Draft Genome Sequence of Sphingobium ummariense Strain RL-3, a
RT Hexachlorocyclohexane-Degrading Bacterium.";
RL Genome Announc. 1:e00956-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQB30076.1}.
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DR EMBL; AUWY01000127; EQB30076.1; -; Genomic_DNA.
DR RefSeq; WP_021319910.1; NZ_AUWY01000127.1.
DR AlphaFoldDB; T0IWD4; -.
DR STRING; 1346791.M529_21725; -.
DR PATRIC; fig|1346791.3.peg.4196; -.
DR eggNOG; COG0693; Bacteria.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000015523; Unassembled WGS sequence.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015523};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 30..227
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 231 AA; 24984 MW; 270EF095EA53D01B CRC64;
MTHILIVLSA ADTWTRADGS LYDSGVWAQE FVDIDEAFMR AGFRVDLASP GGVVPTMDRR
SLDPDVVGDD MAERMRAYLD RHAERIAHPL VLAAIDTGAY DAVVVPGGHG PVEDLYKDPD
MGRVLVEADR AGKVIAAVCH GPAALLAARD EKGRWPFAGR KMTALSDEEE IEFGTAENAP
WLLADTLRKR GAVFEQGPNW RAHVVKDGNL LTGQNPQSSA SLAEVVIAAL R
//
