ID T0L706_9MICR Unreviewed; 196 AA.
AC T0L706;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Exosome complex exonuclease rrp41 {ECO:0000313|EMBL:EQB60299.1};
GN ORFNames=NAPIS_ORF02129 {ECO:0000313|EMBL:EQB60299.1};
OS Vairimorpha apis BRL 01.
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nosematidae;
OC Vairimorpha.
OX NCBI_TaxID=1037528 {ECO:0000313|EMBL:EQB60299.1, ECO:0000313|Proteomes:UP000053780};
RN [1] {ECO:0000313|EMBL:EQB60299.1, ECO:0000313|Proteomes:UP000053780}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRL 01 {ECO:0000313|EMBL:EQB60299.1,
RC ECO:0000313|Proteomes:UP000053780};
RX PubMed=23829473; DOI=10.1186/1471-2164-14-451;
RA Chen Yp., Pettis J.S., Zhao Y., Liu X., Tallon L.J., Sadzewicz L.D., Li R.,
RA Zheng H., Huang S., Zhang X., Hamilton M.C., Pernal S.F.,
RA Melathopoulos A.P., Yan X., Evans J.D.;
RT "Genome sequencing and comparative genomics of honey bee microsporidia,
RT Nosema apis reveal novel insights into host-parasite interactions.";
RL BMC Genomics 14:451-451(2013).
CC -!- SIMILARITY: Belongs to the RNase PH family.
CC {ECO:0000256|ARBA:ARBA00006678}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE647309; EQB60299.1; -; Genomic_DNA.
DR AlphaFoldDB; T0L706; -.
DR VEuPathDB; MicrosporidiaDB:NAPIS_ORF02129; -.
DR HOGENOM; CLU_115515_0_0_1; -.
DR Proteomes; UP000053780; Unassembled WGS sequence.
DR GO; GO:0000176; C:nuclear exosome (RNase complex); IEA:UniProt.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.230.70; GHMP Kinase, N-terminal domain; 1.
DR InterPro; IPR001247; ExoRNase_PH_dom1.
DR InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR PANTHER; PTHR11953; EXOSOME COMPLEX COMPONENT; 1.
DR PANTHER; PTHR11953:SF0; EXOSOME COMPLEX COMPONENT RRP41; 1.
DR Pfam; PF01138; RNase_PH; 1.
DR SUPFAM; SSF55666; Ribonuclease PH domain 2-like; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW Exonuclease {ECO:0000313|EMBL:EQB60299.1};
KW Exosome {ECO:0000256|ARBA:ARBA00022835};
KW Hydrolase {ECO:0000313|EMBL:EQB60299.1};
KW Nuclease {ECO:0000313|EMBL:EQB60299.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053780}.
FT DOMAIN 16..118
FT /note="Exoribonuclease phosphorolytic"
FT /evidence="ECO:0000259|Pfam:PF01138"
SQ SEQUENCE 196 AA; 22892 MW; 7BD2DD4D407AFA98 CRC64;
MFREDGRKKD EIKQIIIKNL NSYTYLKQGN THVRVKSDGP KEGNKLNISM VFSKSSRQEQ
INEKRIFELE TEIYNIFNNI ILTDNNIDIE IEVIQEDGSL ISTIVNCVTL NLCYIGVPLI
DFPCSITYSR FQDLTLCEEQ GRNFFINVVW LMNREKIVYF KSLGRVTQEV LQKINEEGFL
GCKKIYQQLK SFLISI
//
