ID T0MGQ4_9MICR Unreviewed; 567 AA.
AC T0MGQ4;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Serine threonine protein kinase {ECO:0000313|EMBL:EQB60220.1};
GN ORFNames=NAPIS_ORF02226 {ECO:0000313|EMBL:EQB60220.1};
OS Vairimorpha apis BRL 01.
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nosematidae;
OC Vairimorpha.
OX NCBI_TaxID=1037528 {ECO:0000313|EMBL:EQB60220.1, ECO:0000313|Proteomes:UP000053780};
RN [1] {ECO:0000313|EMBL:EQB60220.1, ECO:0000313|Proteomes:UP000053780}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRL 01 {ECO:0000313|EMBL:EQB60220.1,
RC ECO:0000313|Proteomes:UP000053780};
RX PubMed=23829473; DOI=10.1186/1471-2164-14-451;
RA Chen Yp., Pettis J.S., Zhao Y., Liu X., Tallon L.J., Sadzewicz L.D., Li R.,
RA Zheng H., Huang S., Zhang X., Hamilton M.C., Pernal S.F.,
RA Melathopoulos A.P., Yan X., Evans J.D.;
RT "Genome sequencing and comparative genomics of honey bee microsporidia,
RT Nosema apis reveal novel insights into host-parasite interactions.";
RL BMC Genomics 14:451-451(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KE647314; EQB60220.1; -; Genomic_DNA.
DR AlphaFoldDB; T0MGQ4; -.
DR VEuPathDB; MicrosporidiaDB:NAPIS_ORF02226; -.
DR HOGENOM; CLU_030579_0_0_1; -.
DR Proteomes; UP000053780; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR016688; MscS-like_plants/fungi.
DR InterPro; IPR006685; MscS_channel_2nd.
DR PANTHER; PTHR31618:SF7; MECHANOSENSITIVE ION CHANNEL PROTEIN; 1.
DR PANTHER; PTHR31618; MECHANOSENSITIVE ION CHANNEL PROTEIN 5; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EQB60220.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053780};
KW Transferase {ECO:0000313|EMBL:EQB60220.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 143..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 406..464
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 567 AA; 66360 MW; CB0F09AA7F1B2D35 CRC64;
MTEENKENLS LDTNKTPEDN QNNEENENKE NKNTENDDKK EKVNREEIVG DILANNPLVN
PNVQEEEESR TFTKKEVLQS KKFSWLKLNE YLDYKFQFIP VTIRLSLISD NILYISLNIL
DIFKIQINEI VIEILQVVRA TNYYLSMCVT SFLIVLAYHY TINKYILFAN KGGAEFLILT
LVLGYGCTMG LFFIEKFFLN FCTAEIRRRE YRSRIWDINY KIFVFKKLVA ISKAKPHNRK
ELGEEMIPDY DPGFYVKQNG LKLDNKKDAT DIAESIFAYL GVQNITYENL KIYFPENTKE
IYEYLANKKI NEEDNLEPLK FEEISNEAVK LQVEKNDMSR TLVDRESIFN KLDLILSVVV
TYIAVVILLI LFNIDYKVYL ATIGPAFFTF GWIFSDTIKE IYNCFVFLLV KHPYDIGDRV
IIDDKEYIVF RTDVLSSSFI DINGKLCYIP TPVLFNKTIF NIRRSRKQSE ILTLLCGSQT
KFKDAINLKE QLSNSLAEKK HDFTGYVEIY KFEIDGGNIS FSVLIEHISN FQQETEKIKR
REMCVDIVEK TLTKCGITYN NSFKFED
//
