ID T0NEA1_9CLOT Unreviewed; 577 AA.
AC T0NEA1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=M918_01150 {ECO:0000313|EMBL:EQB90231.1};
OS Clostridium sp. BL8.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1354301 {ECO:0000313|EMBL:EQB90231.1, ECO:0000313|Proteomes:UP000015873};
RN [1] {ECO:0000313|EMBL:EQB90231.1, ECO:0000313|Proteomes:UP000015873}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BL8 {ECO:0000313|EMBL:EQB90231.1,
RC ECO:0000313|Proteomes:UP000015873};
RX PubMed=25076986; DOI=10.1186/1757-4749-6-30;
RA Marathe N.P., Shetty S.A., Lanjekar V.B., Rasane M.H., Ranade D.R.,
RA Shouche Y.S.;
RT "Genome sequencing of multidrug resistant novel Clostridium sp. BL8 reveals
RT its potential for pathogenicity.";
RL Gut Pathog. 6:30-30(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQB90231.1}.
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DR EMBL; AUPA01000005; EQB90231.1; -; Genomic_DNA.
DR RefSeq; WP_021281321.1; NZ_AUPA01000005.1.
DR AlphaFoldDB; T0NEA1; -.
DR STRING; 1354301.M918_01150; -.
DR PATRIC; fig|1354301.3.peg.227; -.
DR OrthoDB; 9813394at2; -.
DR Proteomes; UP000015873; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000015873};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 314..547
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 15..42
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 577 AA; 67093 MW; B94D8590C4767DF4 CRC64;
MNFESFTKKQ LIEYIKIKDK KIHELEQVIE SYDKKIQEIT LSENIMRAVF ESTTDGMIVK
DEKFNIININ KGFKDIWELE DKYSNETDKY KLAEYCNDKL ADSEKFLEII DIIEAENREN
LDYIYFKNGK VIERIHQPLK VNGEIRGRVW SFRDITRKRN LEKCLEAGEE LYKRLINRLP
YGVFVYENGK QIIANEAALN FEAEKLKDYN LGDTLKVHPK YRELVEGRIK KLLEGECEVD
FLEQKILLDD GSTWDVEVAG FSFKQEENLY VTAIVRDISD RKKLHKLEMD VLEKSILLEQ
AKEYNELKTQ LFSIVSHELK TPLNIILGGI QLLQKSFDDQ REFEEYYYRG ITNLNFEAKK
KYLTSMKQNC YRLLRLINNF IDMNKIENGF FKLELENKNI INIVENITLS VVDYVESKGI
TLIFDTEVEE RILACDEDKL ERVILNLLSN AIKFTEVGGR IQVNIYDKAE SIVISVKDSG
CGIAKDMHSK IFEPFTQADF LLRRRTEGSG IGLTLVKALI ELHGGTISVR SDLGKGSEFI
IKLPVRLVEN SEVFTGNMDL GDDKVEKITV EFSDIYS
//
