ID T0NI71_9CLOT Unreviewed; 2024 AA.
AC T0NI71;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=M918_18990 {ECO:0000313|EMBL:EQB89765.1};
OS Clostridium sp. BL8.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1354301 {ECO:0000313|EMBL:EQB89765.1, ECO:0000313|Proteomes:UP000015873};
RN [1] {ECO:0000313|EMBL:EQB89765.1, ECO:0000313|Proteomes:UP000015873}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BL8 {ECO:0000313|EMBL:EQB89765.1,
RC ECO:0000313|Proteomes:UP000015873};
RX PubMed=25076986; DOI=10.1186/1757-4749-6-30;
RA Marathe N.P., Shetty S.A., Lanjekar V.B., Rasane M.H., Ranade D.R.,
RA Shouche Y.S.;
RT "Genome sequencing of multidrug resistant novel Clostridium sp. BL8 reveals
RT its potential for pathogenicity.";
RL Gut Pathog. 6:30-30(2014).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQB89765.1}.
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DR EMBL; AUPA01000019; EQB89765.1; -; Genomic_DNA.
DR RefSeq; WP_021281764.1; NZ_AUPA01000019.1.
DR STRING; 1354301.M918_18990; -.
DR PATRIC; fig|1354301.3.peg.669; -.
DR Proteomes; UP000015873; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 3.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF13847; Methyltransf_31; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 3.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000015873}.
FT DOMAIN 766..841
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2024 AA; 233544 MW; BA84E4EF3E276806 CRC64;
MEQVNKGLGH WNDQLKNLKS HEKFLWDYCD KSLYKKCIYK EVFDKEIGNT VSDICKNNNL
LIYTFLVSTL KVTLSKYMGK NNIAIGIPCY SNQNMRGNVH INKLLPLVSY IDPEMTYLEY
MGSIKAKVLE NYKNQSYLSS KILVQNGLVN DVMELSPISI CMKGLHEDID INYICESSKN
ELSFLLDPMK DKSIGIKIVY NSNKITEDTV KALYQSYETA LIDILNNYNK KIKDIKILSQ
KDMEKILHEF NDTKADYPKD KTIHELFQDQ VEKTPDNIAV IFEDKKLTYR ELNERSNSLA
RVLRDKGVKA DSIVGIVVER SLEMIVGIMG ILKAGGAYLP IDPNYPKGRI EYMLKDSGCR
VLLSKNDLVE TIEFNGEIID LYDENLFNRG SSNLEKINNS TKLAYIIYTS GTTGKPKGAM
IEHRSLVNRL NWMQKKYPIT EKDTILQKTT YTFDVSVWEI LWWSLVGAKV CMLTPNGEKD
PMKIIETIDK YEVTTMHFVP SMLDVFLYCV EENRNNINLS SLRQVFSSGE ALNFKQVSKF
YKEFETGKKL INLYGPTEAT IDVAYFDCAS DGKRIIPIGK PIDNTELYIL KNNELVPIGV
AGELYIAGHG LARGYVNRPE LTDEKFVDNP FEHGTKMYKT GDLARWLPDG NIEFLGRIDN
QVKIRGFRIE LGEIENRLLQ HENIKEAAVL VKENKDSEKY ICAYVVSDKK LQELDLKGYL
KETLPEYMVP AYFVQVEKMP LKTNGKLERR ALPEPNLDVT LTEYEAPRNK VEETLSKIWS
EILGVEKVGI NDNFFDLGGH SLKATMLMAK IHKELNKEVP LKELFKMPTI KELSQYIKNA
EESPYSKIEK VEEKEYYEAS SAQKRMYMLQ QFDKNSTAYN MPVAFELKGE VDKWRVEEAF
KKLVKRHEAL RTYFQSNSSE IVQKVQKNYT FELMSKKEEG DIESIIDNFV RPFNLEKAPL
FRVELIENEN KTYLLIDMHH IISDGTSMGI LIKDFENLYN QQDLDLLKLQ YKDFAAWQNG
LLKSQDMKKQ EQYWINMFSD EIPVLNMPTD YKRPDVQSFE GDSVKFVIDK DTTIELKNLA
KETGATIYMV LLSAVNILLS KYSGQEDVIV GSPIAGRKQE NLQNIIGMFV NTLSMRNYPL
GNKTYEEFLT EVKTNCLKAY ENQEYQFEEL VEKLNLKRYS NRNPVFDVMF ILQNMKQYGV
KLNNCSIEQY AYKNKTSKFD LLFIATEYEE KINFEIQYCS GLFKQDTVEK MIKRFKKVLS
NITNNRHVQI SEIDVLLDEE RKKLLIEFNN TDVLYDNTIT IKELFEERVE KTPNDVALVF
KNKTMTYNDV NEYSNNLASY LFHHGNVGNN SKVGILMERS ELMIIAILAT LKVGGTYVPI
DPQYPIDRIK IIAEDCEIRN MISSKEQIPI LNKLQWECSK FQNYICLNCN NVYDVEEFND
SNFMSEDLWN HVVSSSSSKI GEGGWKSSYN GQEFSCEEMK EYSENTLYKL KPYINKDSKV
LEIGCASGLT MFEIAPHVNE YFGTDMSGAV IERNSERVEK GCIKNIKLKC LKAHEINEID
DGDFDVIIIN SVIQYFPGHN YLRSIIEKSL NLLKDKGIIY IGDIMDSELK EDLIESLNEF
KRNNSSHGNK TKIQFDSELF VPRAYFEDIA IDFQEINKIE FSKKIHTIEN ELTKFRYDCV
IEVSKSHSRK CIDKKYKYQH GLMDLMKYKN IPYISNIKSS DLAYILYTSG STGKPKGVEV
QHKAVVNFIN GIVSSINFTN KNAILCATNI SFDIFVLETL LPLILGLKIV IADEEEQINP
QLLKKLIHDW NIDVLQVTPS RMQMIINEDK AVEELKKLKI ILVGGEPLKE TLLKSLSQTT
NASIYNMYGP TETTVWSTFS KQSFTEQITI GKPINNTQIY ILDKYMKLVP IGTSGEMYIS
GDGLAKGYVN NTELTAEKFI KNPFKLQGKM YKTGDFARWL PDGNIEFLGR IDNQVKIRGF
RIELGEIENR LLQHEYIKGV VVLVKENKKN DKKDMCLRSR RKKS
//
