ID   T0P9G8_9CLOT            Unreviewed;       962 AA.
AC   T0P9G8;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   RecName: Full=Carrier domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=M918_13235 {ECO:0000313|EMBL:EQB86563.1};
OS   Clostridium sp. BL8.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1354301 {ECO:0000313|EMBL:EQB86563.1, ECO:0000313|Proteomes:UP000015873};
RN   [1] {ECO:0000313|EMBL:EQB86563.1, ECO:0000313|Proteomes:UP000015873}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BL8 {ECO:0000313|EMBL:EQB86563.1,
RC   ECO:0000313|Proteomes:UP000015873};
RX   PubMed=25076986; DOI=10.1186/1757-4749-6-30;
RA   Marathe N.P., Shetty S.A., Lanjekar V.B., Rasane M.H., Ranade D.R.,
RA   Shouche Y.S.;
RT   "Genome sequencing of multidrug resistant novel Clostridium sp. BL8 reveals
RT   its potential for pathogenicity.";
RL   Gut Pathog. 6:30-30(2014).
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EQB86563.1}.
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DR   EMBL; AUPA01000219; EQB86563.1; -; Genomic_DNA.
DR   AlphaFoldDB; T0P9G8; -.
DR   STRING; 1354301.M918_13235; -.
DR   OrthoDB; 51171at2; -.
DR   Proteomes; UP000015873; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd12117; A_NRPS_Srf_like; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.980; -; 2.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   Pfam; PF00668; Condensation; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000015873}.
FT   DOMAIN          14..447
FT                   /note="Condensation"
FT                   /evidence="ECO:0000259|Pfam:PF00668"
FT   DOMAIN          467..810
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          867..940
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
FT   NON_TER         962
FT                   /evidence="ECO:0000313|EMBL:EQB86563.1"
SQ   SEQUENCE   962 AA;  110418 MW;  1D5074C93C2945F7 CRC64;
     MVKNNKLNKN NIDNFMSLTS LQQGMLFHYI SDEESNMYHE QLSLTLRGDL KLELLRRALQ
     FVIDSNEMLR TIFRWKGIEK PVQVVLKQHE IPIKYLDFTN EEDKEGLIIE VKVEDLNNRI
     DITRETLRIY LCKLDESTHE MIISNHHILY DGWSNGIILK GVMEVYNCLY EEKDFKKLNK
     TRFSQFIKYL NTINKEEEKK YWSNYLEGLD DKDDYFSCKE VGVHKEISYK IDDIKANKIK
     DFSKENKVLL SSILYGAWGI LLQKFNSSNE VLFGTTVSGR PENIGSIDKM VGLFINTIPL
     RVKSDEKTTL IGLINYLDKN LNERKGFENT SLIDIKEYCG LKVNEEIFNS IVTIENYPLD
     LSSNKENILS IEEFSIVEQT NYNMALEILT FDGIEFKFNF NSLSIDESIV EKLGIYLERI
     IENLLNNPNI CIENVDLLSE AEKNQILYEF NDTKADYPKD KTIHELFEAK VEKTPDNMAV
     VFEENKLTYR KLNERANSLA RVLRDKGVKA DSIVGIMVER SLEMIVGIMG ILKAGGAYLP
     IDPNYPKERI EYMLKDSESK ILLSKGDLLE TIEFDGEVID LFSEELFRNE ACNLEKISNS
     SSLAYVIYTS GTTGPPKGVM CEHKNVVRLV KNTNYIGFKE DDKILQTGSM VFDASTFEVW
     GALLNGLELY LAKNETIILP ELLEEFVVRN NITILWLTSE LFNQIAEENI NVFKNLRYLL
     AGGDILSPKY ISLVRKQFTN LKIVNGYGPT ENTTFSTTYL IEKEYSSNIP IGKPIANSQA
     YILDANYNLT PIGVCGELIV SGDGLAKGYL NRPELTAQKF VDNPFEPGTK MYKTGDLARW
     LPDGNIEFLG RIDNQVKIRG FRIELGEIEN RLLQHESIKE AAVLVKENKD GEKYICAYVI
     SDKKLQELDL KGYLKETLPE YMVPAYFVEL EKMPLTANGK LDRRALPEPN LDATLTEYEA
     PR
//