ID T0PDZ7_9CLOT Unreviewed; 223 AA.
AC T0PDZ7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Hydrogenase nickel incorporation protein HypB {ECO:0000313|EMBL:EQB85917.1};
GN ORFNames=M918_16820 {ECO:0000313|EMBL:EQB85917.1};
OS Clostridium sp. BL8.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1354301 {ECO:0000313|EMBL:EQB85917.1, ECO:0000313|Proteomes:UP000015873};
RN [1] {ECO:0000313|EMBL:EQB85917.1, ECO:0000313|Proteomes:UP000015873}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BL8 {ECO:0000313|EMBL:EQB85917.1,
RC ECO:0000313|Proteomes:UP000015873};
RX PubMed=25076986; DOI=10.1186/1757-4749-6-30;
RA Marathe N.P., Shetty S.A., Lanjekar V.B., Rasane M.H., Ranade D.R.,
RA Shouche Y.S.;
RT "Genome sequencing of multidrug resistant novel Clostridium sp. BL8 reveals
RT its potential for pathogenicity.";
RL Gut Pathog. 6:30-30(2014).
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM
CC subfamily. {ECO:0000256|ARBA:ARBA00006211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQB85917.1}.
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DR EMBL; AUPA01000237; EQB85917.1; -; Genomic_DNA.
DR RefSeq; WP_021285579.1; NZ_AUPA01000237.1.
DR AlphaFoldDB; T0PDZ7; -.
DR STRING; 1354301.M918_16820; -.
DR PATRIC; fig|1354301.3.peg.4465; -.
DR OrthoDB; 9802035at2; -.
DR Proteomes; UP000015873; Unassembled WGS sequence.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR GO; GO:0051604; P:protein maturation; IEA:InterPro.
DR CDD; cd05390; HypB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR004392; Hyd_mat_HypB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00073; hypB; 1.
DR PANTHER; PTHR30134:SF2; HYDROGENASE MATURATION FACTOR HYPB; 1.
DR PANTHER; PTHR30134; HYDROGENASE PROTEIN ASSEMBLY PROTEIN, NICKEL CHAPERONE; 1.
DR Pfam; PF02492; cobW; 1.
DR PIRSF; PIRSF005624; Ni-bind_GTPase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nickel {ECO:0000256|ARBA:ARBA00022596};
KW Reference proteome {ECO:0000313|Proteomes:UP000015873};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 38..196
FT /note="CobW/HypB/UreG nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02492"
SQ SEQUENCE 223 AA; 24719 MW; BD8692832B1AF93F CRC64;
MDNYKVLEIK QSVFEDNNKQ ADLLREELKK EKTFLLNLMS SPGSGKTTTV LRTIEALKGE
MNIGVLEADI DSEVDAKTVS KTGAKVIQLH TGGMCHLDAD MTKQGLKGLG TDGIDFVILE
NVGNLVCPAE FDTGASKNAM ILSVPEGDDK PLKYPLMFSI VDVLLINKMD TMSVFDFDLE
AVKERVKKLN PNIKVIPISA KKGEGLEEWV DWIKSEVKNW NEN
//
