ID T0PJD5_SAPDV Unreviewed; 3037 AA.
AC T0PJD5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Myosin-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SDRG_16683 {ECO:0000313|EMBL:EQC25464.1};
OS Saprolegnia diclina (strain VS20).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=1156394 {ECO:0000313|EMBL:EQC25464.1, ECO:0000313|Proteomes:UP000030762};
RN [1] {ECO:0000313|EMBL:EQC25464.1, ECO:0000313|Proteomes:UP000030762}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VS20 {ECO:0000313|EMBL:EQC25464.1,
RC ECO:0000313|Proteomes:UP000030762};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Nusbaum C., Tyler B., van West P., Dieguez-Uribeondo J.,
RA de Bruijn I., Tripathy S., Jiang R., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Saprolegnia declina VS20.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; JH767276; EQC25464.1; -; Genomic_DNA.
DR RefSeq; XP_008621123.1; XM_008622901.1.
DR STRING; 1156394.T0PJD5; -.
DR EnsemblProtists; EQC25464; EQC25464; SDRG_16683.
DR GeneID; 19957410; -.
DR VEuPathDB; FungiDB:SDRG_16683; -.
DR eggNOG; KOG0160; Eukaryota.
DR InParanoid; T0PJD5; -.
DR OMA; FAMENDT; -.
DR OrthoDB; 73855at2759; -.
DR Proteomes; UP000030762; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd17781; CBS_pair_MUG70_1; 3.
DR CDD; cd14890; MYSc_Myo29; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 10.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR13140:SF856; HEAVY CHAIN, UNCONVENTIONAL MYOSIN; 1.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR Pfam; PF00571; CBS; 18.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF00564; PB1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00116; CBS; 19.
DR SMART; SM00015; IQ; 3.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00666; PB1; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 10.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51371; CBS; 16.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51745; PB1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Reference proteome {ECO:0000313|Proteomes:UP000030762};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 3013..3033
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..739
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1207..1265
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 1274..1331
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 1371..1427
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 1547..1606
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 1614..1669
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 1713..1770
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 1879..1936
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 1946..2003
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 2217..2275
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 2284..2341
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 2358..2414
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 2423..2481
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 2517..2576
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 2584..2642
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 2678..2736
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 2744..2802
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 2877..2970
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 619..641
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1149..1191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1524..1549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2181..2216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1161..1190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2181..2203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 126..133
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 3037 AA; 328057 MW; D727D1177BF06914 CRC64;
MASKAKTAKR AERLKKAKAA KESSADLSWQ IDDLLTLSDL SEENLLRSLH SRYEHDLIYT
FVGPILISIN PYRVIDDIYS DATMDLYHKT SGGSKPHVFA TVKAAYEELV LSDVTKPSDQ
SIIISGESGA GKTETTKVIM RYLARVASGQ SSGAATEGSL EQKVLDSNPL LESFGNAKTL
RNDNSSRFGK FIEIQFDRHG KIGGAEIMNF LLEKTRIVTQ NIGERNYHIF YQLLAGADAA
TKSQLHLTRP EDYDYLRKSE CYVIPSKDDE HEFEITRRCL GNIGISQELQ DNVFAMLAAI
LHLGNVDFKV EQETCVPLNA TTLETMSWIA DLLQVSKDAL RNALCNRQLF VGGKVIIQTQ
DANQARDKRD ALAKTIYSSL FLWLVMELNR TISEPSRKWG FIGVLDIYGF EKFDWNTFEQ
LCINFTNEKL QRHFNQHMLE VEQVEYTKEG IDWTHIKFQD NQTTLELLEG KPNGKPGVFI
ALDDVWRTKG EEANRKFVSY LHATFGGNAA HESYIQPKVD AAYSFGIKHY AGDVIYDASG
FNDKNNEDLN DDMKELIKQS GSDWLKTIVD NSLQSTEAVS RRVSAKPAAV SRRPSELPSD
KKTRTLREVS VGAQFRYQLQ ELMAKISAAT PRYIRCIKPN EEKRPMAMDG AQCVRQLKYS
GMMEAIQIRQ KGFGLREEHD TFFYDFLALD PAAEDIHELV ASISEMLNEG KDQWQMGSTK
IFLKRSVAEK LKRLKMLREI SAARTLQRGY HIWKRTQCAI KIQSAVRSWR AQKELGLLRS
AAYTVMKMAR GFAARSKYKR LVVVHRERVA AAVKIQAIAR GFVIRQRDLL HPFAGMGAKE
LDARIKEIEA EIAVAAKKKQ FDKCTSLQKD LDATLEARRL VRTPKEVDAE IAALHDEMDA
LARQKKYAEC SALQTKLDAL EAFRKAMPED LSDLEPAELD ARIDSLNAEL QAAMANRQFD
ACGAIHDRLD KLVAVRKTKQ TPAEMDIEIA NLTVALQTSM AKKQFDKCAS IQADLDAVTK
RRAKAQALLP PPPPAAAPVA AVATKPTTVV KATAAKASAK SASVVMPRAA PSILAPTVSA
PSISAATVSA PVISAPSVAA PTVSVTAPSV SVAPKQQPTM PALTAAPSAT ALVPVGSQAL
VALGSQAIVP KNDRPPRRPR SNSNDSNASS QAISVVSRAS KVSKASTTKP AAIQEAVEDI
SRTVERLRPA KAVTVPETMS VKEAAGVMKS NRTAAVLVVN NAGGLEGILS DTDVTRRVVG
PGLDASKTAV ATVMTPHPSC VTSTDKATQA LNMMLQGRFR HLPVIDANSG AVVGLLNVSK
CLHDAIRRLE HAHTKALALQ KDLNASGSAM ALLAPMLEKM SSPTLYDVIA RDTLPPLVLE
DDMLADVVAA MASSRKAALV VDEDKRLIGI LTPKDVMTRV IAPGLSLTTT RVSKVMTADP
DAAVSGTTIM DAFHIMHDGR FLNLPIVDEN GVVAGLTDVL SLAVHAFSAG DDGHMLTQFV
QASFHHGSDL DELASNASGA SAFSRSSKLS RRTDRSLTSK PTPVSSLRPA PAHTIVETAS
VADVCQLMRA KQTDAVLVVA HDGGLVGIIT DNDICRRVVA QNLNARSTPV SSAMTANIKY
VGPDDSALDA MVLMHEGHFR HLPVVDQSSV VGILSIGKCL FDAIKRMEQA MSATEALQQS
LEQQFKGQMK GMVGSLMDKM FSSSLTLSSL LQTDTGAPAP IVSRTTTVAE AVTLMASSRK
AAIVVENGRL VGVFSPKELV LRVLALGNDP TKTILGDVML VDPEVGLPDT HALEAMQIMH
ETQVLNLPVV SPTGALVGLV DVLTMSYGCF SIVYGDSRDK LEEFWNTTFQ LEAAAPTPLL
TAPGHGANLV QAQRTVASLR PSKAMTILDT TSVRECAKAM ERQGADAALV VSGAGALVGI
VTSTDLTRRV ISLNKSPDST CISAAMTPQP QFVTEDDPAI DALSTMLAGK FRHIPVVDSQ
GLVVGILHIA KCLYDAIRKL EATTKSQAKE LAANTKLVKR LGPMAHRLFS PDVLSIIEHD
TVAAPRVLPY TSIFAASKLM ADTKRAALVV NERGHLLGML TPAELLTNVL AKGRPVHTTA
VCDVMISAPQ VVYGATSVVD AMHAMHETKS LHLAVLRSST EAEVLGLIDI LSLSYGSFAK
GSPADWKAFW ESSLEVDDDG TSSVMSSHSL HSKKSSMHQG GGGKKTSSGD VRPVSKLRPS
PALTVLADVS VRDAAMTMKA DKADAALVVS REGGLLGILT DTDVTRRVVA LGNDPGFITV
ADAMTANPTF VQEADSAMDA MFMMLEGKFR HLPVVDADLR VSGMLKIQKC LYDAIRRLDD
NARGLMSPSL QSILDADAQA MPPLLSATDS ILHAARQMAS SRKAALVVNS QQKLVGILTP
KDVLLRVVGG GLDVLSTPVG DVMTKNPEAI DPSLSVLDAL HLMHENNFLN LPVVHAATGK
IAGLVDVLSL SYGSFSKGSG EWQTFWDLSL SAPDHDENAD SGIKAANNGP VPTVAALRPS
KATILPDTIT VADAALILRR ARVEACNVVN ATGQLVGILT DTDVTRRVLA RDIDPETCLV
STVMTASPTC VRMTDPATDA LNLMLQGHFK HLPVVDANGE VSGMLDISKC LHDAISVMER
AQASADAFAS ELQRGLGHQD TAAKWIEAMR RPTVAMAVEK NMPPPLVGVD TPVREAAKMM
GSSRTAAVVM DGIDVIGMVT PKDLLRKLIA RSLSAETTRV ADVMTPHPLT MPPTSSILEG
LHVMKETREL FVPIVDPTSK RVVGMADVLC LSYSQFASSG DNSPQNAASE WRTFWQSAMA
MQEEMGVHDD FDDTCSVGTI EDFERTEAMA PTMPAVTMAM TAYSELGDSV SVISADQTSI
STNMAGTFLF KVKDHMGHVH RIRSRPDSLE MLKGEVRSKM TLLPSTNIRL KYEDDEGDLA
VVSSDASLMD AVHMAQESKW KSLLLVVDVL DDPARRISTV PEEYEGGERG LPIGVHNGAI
VPKKKTSSSD KSILFAGVGV ALLGVGIAAM AFLKSSK
//
