ID   T0QRF2_SAPDV            Unreviewed;       495 AA.
AC   T0QRF2;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Cytochrome P450 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SDRG_05537 {ECO:0000313|EMBL:EQC37316.1};
OS   Saprolegnia diclina (strain VS20).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Saprolegnia.
OX   NCBI_TaxID=1156394 {ECO:0000313|EMBL:EQC37316.1, ECO:0000313|Proteomes:UP000030762};
RN   [1] {ECO:0000313|EMBL:EQC37316.1, ECO:0000313|Proteomes:UP000030762}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VS20 {ECO:0000313|EMBL:EQC37316.1,
RC   ECO:0000313|Proteomes:UP000030762};
RG   The Broad Institute Genome Sequencing Platform;
RA   Russ C., Nusbaum C., Tyler B., van West P., Dieguez-Uribeondo J.,
RA   de Bruijn I., Tripathy S., Jiang R., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Saprolegnia declina VS20.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; JH767145; EQC37316.1; -; Genomic_DNA.
DR   RefSeq; XP_008609478.1; XM_008611256.1.
DR   AlphaFoldDB; T0QRF2; -.
DR   STRING; 1156394.T0QRF2; -.
DR   EnsemblProtists; EQC37316; EQC37316; SDRG_05537.
DR   GeneID; 19946264; -.
DR   VEuPathDB; FungiDB:SDRG_05537; -.
DR   eggNOG; KOG0157; Eukaryota.
DR   InParanoid; T0QRF2; -.
DR   OMA; RPEYIEY; -.
DR   OrthoDB; 1611592at2759; -.
DR   Proteomes; UP000030762; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24296; CYTOCHROME P450; 1.
DR   PANTHER; PTHR24296:SF8; CYTOCHROME P450 704B1; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|RuleBase:RU000461};
KW   Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000461};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU000461};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030762};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   495 AA;  55266 MW;  3A5054C2B3D2C594 CRC64;
     MVFGFTFAQE TAAAVAVGLA CLLIAKVVVV YRRKARIAKG LAHLPSLPGH KLLGNLVQQG
     EHIHDHYYWK LELFETLGST YAMRVDLLLD GSVCTSSAAN VRHILATNHT NYVKPAMMQR
     ALGELMGSGI FNVNPSASSS WKAQRKILAS LFSTNAIKTL MDTIFLEHTS ALLSEIETLG
     DGALLDVEAT ALSLTTKFTY AMAFGLVFET ENATEFRDLF REASNLSVSR FTQPWYHWLG
     WFMPSEYRLA RVMRRINALC RDTIRTKRLS ATRGDDLLSE LLRRQEAGND MISDTFIRDM
     MMTMMLAGRE TVGSGLAWVI YTVSKHPIVE ARLVSELQAG EISYVGVGCM SYLDAVVRET
     LRLFPPVPYE LKRAVTDDVW PDGTFVPAGT NVEFSPFAMG RNETRWPQAT TFSPERWLND
     APRPSAFEYP VFNAGPRSCV GQTVALLQLK VVVASLYQRF TFDLISPLNE PAFELGIGLF
     SQDSIQVRAR NRDSL
//