ID   T0R713_SAPDV            Unreviewed;       317 AA.
AC   T0R713;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Translation initiation factor eIF2B subunit alpha {ECO:0000256|ARBA:ARBA00044208};
DE   AltName: Full=eIF2B GDP-GTP exchange factor subunit alpha {ECO:0000256|ARBA:ARBA00044236};
GN   ORFNames=SDRG_00450 {ECO:0000313|EMBL:EQC42726.1};
OS   Saprolegnia diclina (strain VS20).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Saprolegnia.
OX   NCBI_TaxID=1156394 {ECO:0000313|EMBL:EQC42726.1, ECO:0000313|Proteomes:UP000030762};
RN   [1] {ECO:0000313|EMBL:EQC42726.1, ECO:0000313|Proteomes:UP000030762}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VS20 {ECO:0000313|EMBL:EQC42726.1,
RC   ECO:0000313|Proteomes:UP000030762};
RG   The Broad Institute Genome Sequencing Platform;
RA   Russ C., Nusbaum C., Tyler B., van West P., Dieguez-Uribeondo J.,
RA   de Bruijn I., Tripathy S., Jiang R., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Saprolegnia declina VS20.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC       {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JH767132; EQC42726.1; -; Genomic_DNA.
DR   RefSeq; XP_008604149.1; XM_008605927.1.
DR   AlphaFoldDB; T0R713; -.
DR   STRING; 1156394.T0R713; -.
DR   EnsemblProtists; EQC42726; EQC42726; SDRG_00450.
DR   GeneID; 19941177; -.
DR   VEuPathDB; FungiDB:SDRG_00450; -.
DR   eggNOG; KOG1466; Eukaryota.
DR   InParanoid; T0R713; -.
DR   OMA; GDWESCK; -.
DR   OrthoDB; 51607at2759; -.
DR   Proteomes; UP000030762; Unassembled WGS sequence.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.1070; Translation initiation factor eIF-2B, N-terminal domain; 1.
DR   InterPro; IPR042528; elF-2B_alpha_N.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR042529; IF_2B-like_C.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   PANTHER; PTHR45860; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA; 1.
DR   PANTHER; PTHR45860:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE   3: Inferred from homology;
KW   Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030762}.
SQ   SEQUENCE   317 AA;  34105 MW;  B160EDF37EC22A8E CRC64;
     MSTKVVDDFL AYLQDPDSAI AVAVIKALTG VVQRSSASTM MEIESALTEA AAQLKAAADG
     PAPTQALSSI SVTAVCQLFL RYVTRCFLEF DDFDQCKSQL IDRGKLFAET SLLSRKRIAD
     LGHNFVRDGM QVLTHGASRV VTGLLLQAAK TKHFSVLVTE GRPNGAGYKT AEVLSKAGIP
     TTVIVDAAMG YYMEKVDMVI VGAEGVVENG GIVNKIGTFS AAMIAHAMKK PFYVAAESYK
     FARLYPLNQS DFPHSRKDDM SNLPACACRP KTTAQANLTV GSPSCDYTPP HYISLLFTDL
     GVLTPSAVSD ELIKLYQ
//