ID   T0S0F2_SAPDV            Unreviewed;       833 AA.
AC   T0S0F2;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Peptidase M14 carboxypeptidase A domain-containing protein {ECO:0000259|Pfam:PF00246};
GN   ORFNames=SDRG_04119 {ECO:0000313|EMBL:EQC38408.1};
OS   Saprolegnia diclina (strain VS20).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Saprolegnia.
OX   NCBI_TaxID=1156394 {ECO:0000313|EMBL:EQC38408.1, ECO:0000313|Proteomes:UP000030762};
RN   [1] {ECO:0000313|EMBL:EQC38408.1, ECO:0000313|Proteomes:UP000030762}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VS20 {ECO:0000313|EMBL:EQC38408.1,
RC   ECO:0000313|Proteomes:UP000030762};
RG   The Broad Institute Genome Sequencing Platform;
RA   Russ C., Nusbaum C., Tyler B., van West P., Dieguez-Uribeondo J.,
RA   de Bruijn I., Tripathy S., Jiang R., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Saprolegnia declina VS20.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M14 family.
CC       {ECO:0000256|ARBA:ARBA00005988}.
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DR   EMBL; JH767141; EQC38408.1; -; Genomic_DNA.
DR   RefSeq; XP_008608000.1; XM_008609778.1.
DR   AlphaFoldDB; T0S0F2; -.
DR   STRING; 1156394.T0S0F2; -.
DR   EnsemblProtists; EQC38408; EQC38408; SDRG_04119.
DR   GeneID; 19944846; -.
DR   VEuPathDB; FungiDB:SDRG_04119; -.
DR   eggNOG; KOG3641; Eukaryota.
DR   InParanoid; T0S0F2; -.
DR   OMA; CHALTTY; -.
DR   OrthoDB; 168164at2759; -.
DR   Proteomes; UP000030762; Unassembled WGS sequence.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 2.60.40.3120; -; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR000834; Peptidase_M14.
DR   PANTHER; PTHR12756; CYTOSOLIC CARBOXYPEPTIDASE; 1.
DR   PANTHER; PTHR12756:SF45; CYTOSOLIC CARBOXYPEPTIDASE NNA1; 1.
DR   Pfam; PF00246; Peptidase_M14; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030762}.
FT   DOMAIN          324..460
FT                   /note="Peptidase M14 carboxypeptidase A"
FT                   /evidence="ECO:0000259|Pfam:PF00246"
FT   REGION          678..710
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        682..698
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   833 AA;  92916 MW;  7AC3F71B28581B3D CRC64;
     MEVPSSPKPS PRLSLPRAKL KSLLALSSLA PLPLIQAHHE SINDNDAHVA KAEFNTVLPH
     VVHKDIFAAS AEGSPIGSED ESRQLAHLLA EFERRFWKKA NKKATSSLVF RRRSLDPTHV
     ATDEAPVVDP TSLTFDSNFE SANLASAYRV HDRNYSFVSQ CTSKHGDTAG PSRVDQEYDL
     YCTNDTYTLG HIQWYYFKVT RPPGNGRLRV RFNLRNMMKR DSLYNCGMLP AVYSEAKVNA
     GIAGWTHGGE EAFYYQNADV YTRVRRGLRR NFSHYTLSFI YTFEPSEDVV YFAHCFPYTY
     TYLQTYLTSL EKCPLRSRNL RRRTLCSTLC GNACDMLTIT EFTSEPQVLR KRTGVVLTAR
     VHPGETNGSF LLHGIMEFLT GFSDEAIALR KCYIFKIIPM LNPDGVVHGN YRCSLAGIDL
     NRRWSQPSEL YHPTIYAAKK MIALMRQSRK VLLFCDFHGH SRKKNMFTYI AIKMTILSVT
     DRNRYGCKPY LSWSRLEDAK VRLFPYVLCK TSSAQAGGYF SFTDCTFNVT RSKRSTGRVA
     VWSDIQILNS ITLEASFCGT GDNKARRSIA AFATTTPNHT PRHFTQRDFT CSGEQFCHAL
     TTYGALLGIE PIDATTLLGA SAAKHEGVLE LLDLDETPIE PNVRDPTLLT STTAFGANDF
     AYSETALSLL DEIASCVPSP SDGAAESENS SGSDSNPSED NYEPEELESN TAWQAFRRNV
     VLRRSSSALK SASAGPNSGR TASLTLSSSL AKKSIKLRKK VRRSSTTGTP RVTVSDAPAV
     VAKADGGPHR SPRVAPLPLR RVEVKNAGGF AQFHKNMIQR RIHQSQIVMR PPP
//