ID   T0S522_SAPDV            Unreviewed;       773 AA.
AC   T0S522;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Alpha-N-acetylglucosaminidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SDRG_02871 {ECO:0000313|EMBL:EQC40223.1};
OS   Saprolegnia diclina (strain VS20).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Saprolegnia.
OX   NCBI_TaxID=1156394 {ECO:0000313|EMBL:EQC40223.1, ECO:0000313|Proteomes:UP000030762};
RN   [1] {ECO:0000313|EMBL:EQC40223.1, ECO:0000313|Proteomes:UP000030762}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VS20 {ECO:0000313|EMBL:EQC40223.1,
RC   ECO:0000313|Proteomes:UP000030762};
RG   The Broad Institute Genome Sequencing Platform;
RA   Russ C., Nusbaum C., Tyler B., van West P., Dieguez-Uribeondo J.,
RA   de Bruijn I., Tripathy S., Jiang R., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Saprolegnia declina VS20.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; JH767137; EQC40223.1; -; Genomic_DNA.
DR   RefSeq; XP_008606697.1; XM_008608475.1.
DR   AlphaFoldDB; T0S522; -.
DR   STRING; 1156394.T0S522; -.
DR   EnsemblProtists; EQC40223; EQC40223; SDRG_02871.
DR   GeneID; 19943598; -.
DR   VEuPathDB; FungiDB:SDRG_02871; -.
DR   eggNOG; KOG2233; Eukaryota.
DR   InParanoid; T0S522; -.
DR   OMA; GKACFIV; -.
DR   OrthoDB; 1112009at2759; -.
DR   Proteomes; UP000030762; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 1.20.120.670; N-acetyl-b-d-glucoasminidase; 1.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR007781; NAGLU.
DR   InterPro; IPR024732; NAGLU_C.
DR   InterPro; IPR024240; NAGLU_N.
DR   InterPro; IPR024733; NAGLU_tim-barrel.
DR   PANTHER; PTHR12872; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR   PANTHER; PTHR12872:SF1; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR   Pfam; PF05089; NAGLU; 1.
DR   Pfam; PF12972; NAGLU_C; 1.
DR   Pfam; PF12971; NAGLU_N; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030762};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..773
FT                   /note="Alpha-N-acetylglucosaminidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004584337"
FT   DOMAIN          30..113
FT                   /note="Alpha-N-acetylglucosaminidase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12971"
FT   DOMAIN          128..463
FT                   /note="Alpha-N-acetylglucosaminidase tim-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF05089"
FT   DOMAIN          472..735
FT                   /note="Alpha-N-acetylglucosaminidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12972"
SQ   SEQUENCE   773 AA;  85739 MW;  C0504D909C42574A CRC64;
     MRRAIVAVIM LHAALVAALL PRPEHDMISA TKGLIARRLG PAYVDQFVLE ALPVDHISGL
     DIAHVDATPG QVHLRASSAT AMGFGLHAYL KAAAQTQTNW EDDPLVLPPT LPALTVPLRL
     GRQAAYTYYE NVCTFSYSQW SWSWAQWERH IDWMALNGIN VPLAFTGQEK VWATTFGAFN
     VSASGLDGFF AGASFLAWGR MGNVQGSWVR GPLPRSFIEQ QFELQTKILA RMRAFGMTPA
     LPAFAGHVPA EMVSLYPNAK FVQSPPWIGF KPPFTSVYML DPTDPLFVEI GAAFLRHQAS
     LLNYTAILYQ TDTYNEMDPA FSARTYLAAS SSAVLKSMRA VHPSAVWLMQ GWLFSFSRFW
     TATRVRDYIA HLPQDGLIVL DLYSEVKPVW QTTDNYFGKY WIYCVLHNFG GSLGMRGDLP
     TIASDLVAAR TASAGTLLGL GLTMEGIYQN YIVYDLALQM PWQASALDVP TYVDAFIRAR
     YHHPTQNALD AWQRLAATVY NVSKGFGGVT KCIVSLRPRW GLLQSRFMPT ALAHNAEDVL
     FAWRRLLAAA PALASHLSFT RDLVDVTRQV LSDGLAADVA ALETLFHAQV APLAELDAVM
     RRMQDAMEML ERILNTNRHF MLGPWLADAR ALGGADDAAY FEYEAKNQVT RWGDANGNAL
     SDYASKDWGG LVSSYYLPRW RIWWRHVRSA YVARSAVDHA AVHAALEAFE LAWQLERLEL
     PVEPVEDSVS VALAIAKTLL PDDDVGAAVV KDAAPSFARD QVLARACLLD CLW
//