ID T0TU94_9STRE Unreviewed; 345 AA.
AC T0TU94;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=N-acetylmuramoyl-L-alanine amidase {ECO:0000313|EMBL:EQC74636.1};
DE EC=3.5.1.28 {ECO:0000313|EMBL:EQC74636.1};
DE Flags: Fragment;
GN ORFNames=HSISS2_1400 {ECO:0000313|EMBL:EQC74636.1};
OS Streptococcus sp. HSISS2.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1316411 {ECO:0000313|EMBL:EQC74636.1};
RN [1] {ECO:0000313|EMBL:EQC74636.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HSISS2 {ECO:0000313|EMBL:EQC74636.1};
RA Van den Bogert B., Boekhorst J., Herrmann R., Smid E.J., Zoetendal E.G.,
RA Kleerebezem M.;
RT "Comparative Genomics Analysis of Streptococcus Isolates from the Human
RT Small Intestine Reveals their Adaptation to a Highly Dynamic Ecosystem.";
RL PLoS ONE 8:E83418-E83418(2013).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 73 family.
CC {ECO:0000256|ARBA:ARBA00010266}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQC74636.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ASKC01000061; EQC74636.1; -; Genomic_DNA.
DR AlphaFoldDB; T0TU94; -.
DR HOGENOM; CLU_805434_0_0_9; -.
DR Proteomes; UP000015938; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0004040; F:amidase activity; IEA:InterPro.
DR GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:UniProtKB-EC.
DR Gene3D; 1.10.530.10; -; 1.
DR Gene3D; 2.60.40.3760; -; 1.
DR InterPro; IPR013688; GBS_Bsp-like.
DR InterPro; IPR002901; MGlyc_endo_b_GlcNAc-like_dom.
DR PANTHER; PTHR33308; PEPTIDOGLYCAN HYDROLASE FLGJ; 1.
DR PANTHER; PTHR33308:SF9; PEPTIDOGLYCAN HYDROLASE FLGJ; 1.
DR Pfam; PF08481; GBS_Bsp-like; 1.
DR Pfam; PF01832; Glucosaminidase; 1.
DR PRINTS; PR01002; FLGFLGJ.
DR SMART; SM00047; LYZ2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EQC74636.1};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 113..269
FT /note="Mannosyl-glycoprotein endo-beta-N-
FT acetylglucosamidase-like"
FT /evidence="ECO:0000259|SMART:SM00047"
FT REGION 18..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 345
FT /evidence="ECO:0000313|EMBL:EQC74636.1"
SQ SEQUENCE 345 AA; 37649 MW; BAAE74C40DC9054F CRC64;
MLFLGTCGVT AGADEVMENP SNANATKPIS KEQTTSSTTV SNSETVPKGE KQTSEVTFEN
SYTTVTAEAS FNTVDQNSTE TVFQDKADYI VASNLTNNSV TRSAYQGPDS VDSTSESQSH
FLNAIKQGAM DGAKEGVLPS ITAAQAILES GWGNSSLAQA PNHNLFGIKD SDDWGGDTVV
VPTQEYLNGR YITINAAFRK YSSWNDSVVD HAKFFTSTEW RKNNYRKVIN ATDYRTAAQE
LKNAGYATDP GYAGKLIRLI EAYKLYEWDE ESNTAINISD NPIEIQNNPK AELAITGLNN
ATGSYDLVIS NLVAPYGFKE VLVPTWSEKN GQDDIIWYKA AKQAN
//
