ID   T0U4Q5_9STRE            Unreviewed;       641 AA.
AC   T0U4Q5;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=DUF2207 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HSISM1_975 {ECO:0000313|EMBL:EQC78291.1};
OS   Streptococcus sp. HSISM1.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1316408 {ECO:0000313|EMBL:EQC78291.1};
RN   [1] {ECO:0000313|EMBL:EQC78291.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HSISM1 {ECO:0000313|EMBL:EQC78291.1};
RA   Van den Bogert B., Boekhorst J., Herrmann R., Smid E.J., Zoetendal E.G.,
RA   Kleerebezem M.;
RT   "Comparative Genomics Analysis of Streptococcus Isolates from the Human
RT   Small Intestine Reveals their Adaptation to a Highly Dynamic Ecosystem.";
RL   PLoS ONE 8:E83418-E83418(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EQC78291.1}.
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DR   EMBL; ASKI01000009; EQC78291.1; -; Genomic_DNA.
DR   AlphaFoldDB; T0U4Q5; -.
DR   PATRIC; fig|1316408.3.peg.2012; -.
DR   eggNOG; COG4907; Bacteria.
DR   HOGENOM; CLU_026556_2_0_9; -.
DR   Proteomes; UP000015933; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR018702; DUF2207.
DR   InterPro; IPR048389; YciQ-like_C.
DR   Pfam; PF09972; DUF2207; 1.
DR   Pfam; PF20990; DUF2207_C; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..641
FT                   /note="DUF2207 domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004572616"
FT   TRANSMEM        250..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        460..481
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        487..506
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          30..210
FT                   /note="DUF2207"
FT                   /evidence="ECO:0000259|Pfam:PF09972"
FT   DOMAIN          289..567
FT                   /note="Predicted membrane protein YciQ-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF20990"
SQ   SEQUENCE   641 AA;  73752 MW;  BF4031151D574B83 CRC64;
     MKRFLLMISL IWSLVCTITI AHADDEVRYS IESYVGHLQL QEDSQATFTQ EITYQFQTGY
     HGQYVTLGSA DPLPKGFKIH RHPEVEAYVD GEKREIRVEE TDLEDGRQLK IYNARIVGGT
     VKIKVKWKID HLLTFYKDIA ELNWFPISDG DEKVAKLDFY VDGLNAKQGK LYAHTGYFNP
     PAQVERTATG YHIWTKDFPK NGKLELHAYW PMTEVLRRDQ ANEINQGNGK EKFLNKEKSI
     EQKTFFYRTL LLKVVPIVSV LLFILAFIPW IRYFISTRTR RISKGVRLYE PPQNLPPFVL
     AKALYQLDFE RMVMSREKGQ LTFNHLIQAT VLDLIDRGNL RLTRDENGET LTCLHYEGLA
     DFELKFIEMI FDQESKINIR EVFSKYKIDK VALKKDFRAA KSDTQRDRIR KIGNDVQSLL
     KKDAQQLSKG VEKEIVKLGL PSYFRDLSEK EEALSKTGCA LHFWLLLILF VSMCFLSFGF
     GSHLSSFYFW MIVLLVVLFI PFYILVKIRE EHLQSLENLD AQFQWMAFRN MIESIPNFNQ
     AELESVVLWN RILVYATMYG QAKKVSQVLK NHQISLPYED WDAVVWITTS SNSFLDGSTL
     MSYADDSYSV SSFSTNSSDG SGGFDGGGFS DGGGGGGFGA F
//