ID T1ED05_HELRO Unreviewed; 272 AA.
AC T1ED05;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=PWI domain-containing protein {ECO:0000259|Pfam:PF01480};
GN Name=20194457 {ECO:0000313|EnsemblMetazoa:HelroP100565};
GN ORFNames=HELRODRAFT_100565 {ECO:0000313|EMBL:ESO01239.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP100565, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO01239.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP100565}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01005028; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096785; ESO01239.1; -; Genomic_DNA.
DR RefSeq; XP_009020475.1; XM_009022227.1.
DR AlphaFoldDB; T1ED05; -.
DR EnsemblMetazoa; HelroT100565; HelroP100565; HelroG100565.
DR GeneID; 20194457; -.
DR KEGG; hro:HELRODRAFT_100565; -.
DR CTD; 20194457; -.
DR eggNOG; KOG2135; Eukaryota.
DR HOGENOM; CLU_1025151_0_0_1; -.
DR InParanoid; T1ED05; -.
DR OrthoDB; 5406435at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR Gene3D; 1.20.1390.10; PWI domain; 1.
DR InterPro; IPR002483; PWI_dom.
DR InterPro; IPR045137; RBM26/27.
DR PANTHER; PTHR14398; RNA RECOGNITION RRM/RNP DOMAIN; 1.
DR PANTHER; PTHR14398:SF0; ZINC FINGER PROTEIN SWM; 1.
DR Pfam; PF01480; PWI; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 7..75
FT /note="PWI"
FT /evidence="ECO:0000259|Pfam:PF01480"
FT REGION 80..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..185
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..252
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 272 AA; 31684 MW; 8E37DB90FB53C776 CRC64;
MQIEDKEALK SWLLDELQPI YDAEPTSLAD YVIALLKKNK NEKDLMDSCL EKLQVFLNEK
THCFVESLFE VLQSKKYLPD TSKTSYSSKD RLSRTTGQQQ HPQMSTATHH SSHHHQQQQH
LHQQQQQHQQ HHHAVSYKNM PKRDQEQIRP SDFAGASSSR YHRYDRSRRD DYDLSRERGS
RKSLKDTQHQ SPCSKFRNNS RDRLRKSIEN ARLKSSETYR ELLSPPLRLP ACARKRSSRS
ISRSDGRGTS RRSYESKLSV TSSRSSSSEG TP
//
