ID T1EDD1_HELRO Unreviewed; 373 AA.
AC T1EDD1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=UDENN domain-containing protein {ECO:0000259|PROSITE:PS50211};
GN Name=20194583 {ECO:0000313|EnsemblMetazoa:HelroP102916};
GN ORFNames=HELRODRAFT_102916 {ECO:0000313|EMBL:ESN94928.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP102916, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN94928.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP102916}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01007075; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMQM01007076; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097558; ESN94928.1; -; Genomic_DNA.
DR RefSeq; XP_009027048.1; XM_009028800.1.
DR AlphaFoldDB; T1EDD1; -.
DR STRING; 6412.T1EDD1; -.
DR EnsemblMetazoa; HelroT102916; HelroP102916; HelroG102916.
DR GeneID; 20194583; -.
DR KEGG; hro:HELRODRAFT_102916; -.
DR CTD; 20194583; -.
DR eggNOG; KOG3569; Eukaryota.
DR HOGENOM; CLU_008196_5_0_1; -.
DR InParanoid; T1EDD1; -.
DR OMA; CGLENER; -.
DR OrthoDB; 5398783at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.200; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR037516; Tripartite_DENN.
DR PANTHER; PTHR15288; DENN DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR15288:SF0; UDENN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR PROSITE; PS50211; DENN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 97..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..320
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
SQ SEQUENCE 373 AA; 43228 MW; 73562991CCBA1756 CRC64;
MFSFFLTTAT GDRKFCWCFR FLPTDTNIPE AICIVSAIGE TCLYQQLLRV LKQAREYSAA
LARQTMQAAY KLKFPKVKKE LYIVAEVCVR ACLYVCLFVR SFVCLFVCSF ALGLLLQLMA
TILLERKVIL VARRISTLSS CIMSICTLLY PFSWPHTLIT VLPPSLADVI DSPAPYILGV
LSCFKHLLEE YQLSEVLIVN LDEGYFMKWM GDEGHILPKK IQRALMLALS DVHLAHDNTG
KTACITDVTM TEAFVRMFVE MCGHYCDFIR YDANKSSLFQ REEFVRAVSS NSIRLFLDWF
SRTPMFQVFI TDRLKENTNQ DLFDQRIKEY RREMEYLSNN KAANMKVIRD KLLNFFKNYG
TKLKKTMKKN SYV
//
