ID T1EG05_HELRO Unreviewed; 251 AA.
AC T1EG05;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=TBCC domain-containing protein 1 {ECO:0000256|ARBA:ARBA00017559};
GN Name=20195507 {ECO:0000313|EnsemblMetazoa:HelroP114291};
GN ORFNames=HELRODRAFT_114291 {ECO:0000313|EMBL:ESN97208.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP114291, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN97208.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP114291}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm,
CC cytoskeleton, spindle pole {ECO:0000256|ARBA:ARBA00004647}.
CC -!- SIMILARITY: Belongs to the TBCC family.
CC {ECO:0000256|ARBA:ARBA00008848}.
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DR EMBL; AMQM01006394; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097417; ESN97208.1; -; Genomic_DNA.
DR RefSeq; XP_009024703.1; XM_009026455.1.
DR AlphaFoldDB; T1EG05; -.
DR STRING; 6412.T1EG05; -.
DR EnsemblMetazoa; HelroT114291; HelroP114291; HelroG114291.
DR GeneID; 20195507; -.
DR KEGG; hro:HELRODRAFT_114291; -.
DR CTD; 20195507; -.
DR eggNOG; KOG4416; Eukaryota.
DR HOGENOM; CLU_077698_0_0_1; -.
DR InParanoid; T1EG05; -.
DR OMA; RMEYCAN; -.
DR OrthoDB; 3019544at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR Gene3D; 2.160.20.70; -; 1.
DR InterPro; IPR017901; C-CAP_CF_C-like.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR036223; CAP_C_sf.
DR InterPro; IPR006599; CARP_motif.
DR InterPro; IPR039589; TBCC1.
DR InterPro; IPR012945; Tubulin-bd_cofactor_C_dom.
DR PANTHER; PTHR16052:SF0; TBCC DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR16052; UNCHARACTERIZED; 1.
DR Pfam; PF07986; TBCC; 1.
DR SMART; SM00673; CARP; 2.
DR SUPFAM; SSF69340; C-terminal domain of adenylylcyclase associated protein; 1.
DR PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 1..133
FT /note="C-CAP/cofactor C-like"
FT /evidence="ECO:0000259|PROSITE:PS51329"
SQ SEQUENCE 251 AA; 28142 MW; 2762B3BB7D713891 CRC64;
MTLARSSGTL CQSAVKISKC NDSFIYLLSP LRSVLIEKCQ RSTIILGAVE TSVDVNKSEH
ITVIAATRRF SAQGCKSCNI HLLTPNTPLL FNTNSNITFG PYHTFYPNLE EHMYAAGLAP
LPNLWDQPHV LGSSGLDDDK IFEIQKPSDF FTFTIPFQME GKTKEIPVGL PSKYQKALNQ
RLQKVEDWHK LMGETSMTSD QKKLLHRTVQ AKFQEWLQTT GQARLLQDLV VPQQKAEASS
SLQSLDKLSL D
//
