ID T1EIX5_HELRO Unreviewed; 51 AA.
AC T1EIX5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Mitotic-spindle organizing protein 1 {ECO:0008006|Google:ProtNLM};
GN Name=20196525 {ECO:0000313|EnsemblMetazoa:HelroP138770};
GN ORFNames=HELRODRAFT_138770 {ECO:0000313|EMBL:ESO06264.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP138770, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO06264.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP138770}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- FUNCTION: Required for gamma-tubulin complex recruitment to the
CC centrosome. {ECO:0000256|ARBA:ARBA00002669}.
CC -!- SIMILARITY: Belongs to the MOZART1 family.
CC {ECO:0000256|ARBA:ARBA00011015}.
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DR EMBL; AMQM01000596; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096324; ESO06264.1; -; Genomic_DNA.
DR RefSeq; XP_009015632.1; XM_009017384.1.
DR AlphaFoldDB; T1EIX5; -.
DR STRING; 6412.T1EIX5; -.
DR EnsemblMetazoa; HelroT138770; HelroP138770; HelroG138770.
DR GeneID; 20196525; -.
DR KEGG; hro:HELRODRAFT_138770; -.
DR CTD; 20196525; -.
DR eggNOG; ENOG502S6UI; Eukaryota.
DR HOGENOM; CLU_160285_0_0_1; -.
DR InParanoid; T1EIX5; -.
DR OMA; NSPCASE; -.
DR OrthoDB; 48528at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IBA:GO_Central.
DR GO; GO:0000930; C:gamma-tubulin complex; IBA:GO_Central.
DR GO; GO:0000931; C:gamma-tubulin ring complex; IEA:InterPro.
DR GO; GO:0031021; C:interphase microtubule organizing center; IBA:GO_Central.
DR GO; GO:0005819; C:spindle; IBA:GO_Central.
DR GO; GO:0033566; P:gamma-tubulin complex localization; IEA:InterPro.
DR GO; GO:0051415; P:microtubule nucleation by interphase microtubule organizing center; IBA:GO_Central.
DR GO; GO:0090307; P:mitotic spindle assembly; IBA:GO_Central.
DR InterPro; IPR022214; MZT1.
DR PANTHER; PTHR28520; MITOTIC-SPINDLE ORGANIZING PROTEIN 1; 1.
DR PANTHER; PTHR28520:SF2; MITOTIC-SPINDLE ORGANIZING PROTEIN 1; 1.
DR Pfam; PF12554; MOZART1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
SQ SEQUENCE 51 AA; 5453 MW; 3676839A6FA819F0 CRC64;
VSVLLEISNL LNTGLDAETL SICVRLCEAG VNAEALALVV QELRREVSSL K
//
