ID T1EJH8_HELRO Unreviewed; 115 AA.
AC T1EJH8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=H15 domain-containing protein {ECO:0000259|PROSITE:PS51504};
GN Name=20196728 {ECO:0000313|EnsemblMetazoa:HelroP144985};
GN ORFNames=HELRODRAFT_144985 {ECO:0000313|EMBL:ESO04450.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP144985, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO04450.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP144985}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01004375; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096502; ESO04450.1; -; Genomic_DNA.
DR RefSeq; XP_009017719.1; XM_009019471.1.
DR AlphaFoldDB; T1EJH8; -.
DR STRING; 6412.T1EJH8; -.
DR EnsemblMetazoa; HelroT144985; HelroP144985; HelroG144985.
DR GeneID; 20196728; -.
DR KEGG; hro:HELRODRAFT_144985; -.
DR CTD; 20196728; -.
DR eggNOG; KOG4012; Eukaryota.
DR HOGENOM; CLU_052897_7_2_1; -.
DR InParanoid; T1EJH8; -.
DR OrthoDB; 2878662at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0031492; F:nucleosomal DNA binding; IBA:GO_Central.
DR GO; GO:0030261; P:chromosome condensation; IBA:GO_Central.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IBA:GO_Central.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR CDD; cd00073; H15; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005818; Histone_H1/H5_H15.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11467; HISTONE H1; 1.
DR PANTHER; PTHR11467:SF154; HISTONE H1.0; 1.
DR Pfam; PF00538; Linker_histone; 1.
DR SMART; SM00526; H15; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51504; H15; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 13..89
FT /note="H15"
FT /evidence="ECO:0000259|PROSITE:PS51504"
FT REGION 92..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 115 AA; 12120 MW; 5013A6279B7405DF CRC64;
KSAAAASTKK VVEHPSYNEM VRQALVALKE RGGSSRQAIL KYLMANFKVG SDEHSVNTHL
KVALRNGVKS ETLKQSKGSG ASGSFRLGAA KDTNKNVAKP KKDAVAIKTK AAASP
//
