ID T1EN19_HELRO Unreviewed; 225 AA.
AC T1EN19;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESO12171.1, ECO:0000313|EnsemblMetazoa:HelroP158634};
GN Name=20197969 {ECO:0000313|EnsemblMetazoa:HelroP158634};
GN ORFNames=HELRODRAFT_158634 {ECO:0000313|EMBL:ESO12171.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP158634, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO12171.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP158634}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 5'(3')-deoxyribonucleotidase family.
CC {ECO:0000256|ARBA:ARBA00009589}.
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DR EMBL; AMQM01000093; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB095811; ESO12171.1; -; Genomic_DNA.
DR RefSeq; XP_009008891.1; XM_009010643.1.
DR AlphaFoldDB; T1EN19; -.
DR EnsemblMetazoa; HelroT158634; HelroP158634; HelroG158634.
DR GeneID; 20197969; -.
DR KEGG; hro:HELRODRAFT_158634; -.
DR CTD; 20197969; -.
DR eggNOG; KOG2469; Eukaryota.
DR HOGENOM; CLU_1231081_0_0_1; -.
DR InParanoid; T1EN19; -.
DR OrthoDB; 3108246at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR008380; HAD-SF_hydro_IG_5-nucl.
DR InterPro; IPR023214; HAD_sf.
DR PANTHER; PTHR12103; 5'-NUCLEOTIDASE DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR12103:SF12; 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF05761; 5_nucleotid; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
SQ SEQUENCE 225 AA; 26274 MW; 948913A5370DE132 CRC64;
MGLVLCQDVI MIAKSGHYIS NCPHPWIISE YSSNPPSYNV WPDVVEAIRH VYIPNPLKAE
YGSFFDKWVK DTSRYVRKCS TSMKSWLRMM RHNNGKARPM FLLTSAYQDF AEATLKFVLG
ALKQYISHFN RERWEEFFDF SIFHAEKPMF FNKKNPFYST SVDCNTKVVA DQLEGNRKVL
GGNFTQLDKH LQLVTGKQNP KKCVKKSKIR VKKRNSRFSS QKIIL
//
