ID T1ESH3_HELRO Unreviewed; 308 AA.
AC T1ESH3;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Tetraspanin {ECO:0008006|Google:ProtNLM};
GN Name=20199523 {ECO:0000313|EnsemblMetazoa:HelroP162304};
GN ORFNames=HELRODRAFT_162304 {ECO:0000313|EMBL:ESN98844.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP162304, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN98844.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP162304}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01001067; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097143; ESN98844.1; -; Genomic_DNA.
DR RefSeq; XP_009022794.1; XM_009024546.1.
DR AlphaFoldDB; T1ESH3; -.
DR EnsemblMetazoa; HelroT162304; HelroP162304; HelroG162304.
DR GeneID; 20199523; -.
DR KEGG; hro:HELRODRAFT_162304; -.
DR CTD; 20199523; -.
DR HOGENOM; CLU_903929_0_0_1; -.
DR InParanoid; T1ESH3; -.
DR OrthoDB; 5390965at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR Pfam; PF00335; Tetraspanin; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 283..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 308 AA; 34532 MW; D91BA74C5BF72844 CRC64;
MADFCNKILL TLVNVFVLLC GLMLLTFTIV AFGESPAMDG VLGNSKQIIE TVSRILNVGG
TPDGIFSLTL VMGLSLIFFS LCGIFGSLRN IRILLLIYWV TLLLVIILEF SMIIYASVKL
NTSNVYEIMR NNLKEYHPEV IMDNRTIIPP EHKLSHTWYA TQFLILAVVP PSCCENETTE
IPVNDIVSFS FYDNLPACLK GNKRLINDQG CADVVTSYLH NYSQFICIFC SILLSVELMS
LLGAIDLWNS VKQVSLLSKN NMDKRRNRES ENVYDGRQKI ANSKLSTNDP QSNKSSLISS
ISSYDRSI
//
