ID T1EVT0_HELRO Unreviewed; 612 AA.
AC T1EVT0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=BACK domain-containing protein {ECO:0000259|SMART:SM00875};
GN Name=20200680 {ECO:0000313|EnsemblMetazoa:HelroP164779};
GN ORFNames=HELRODRAFT_164779 {ECO:0000313|EMBL:ESN92690.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP164779, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN92690.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP164779}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01001824; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097639; ESN92690.1; -; Genomic_DNA.
DR RefSeq; XP_009028997.1; XM_009030749.1.
DR AlphaFoldDB; T1EVT0; -.
DR STRING; 6412.T1EVT0; -.
DR EnsemblMetazoa; HelroT164779; HelroP164779; HelroG164779.
DR GeneID; 20200680; -.
DR KEGG; hro:HELRODRAFT_164779; -.
DR CTD; 20200680; -.
DR eggNOG; KOG4441; Eukaryota.
DR HOGENOM; CLU_018559_0_0_1; -.
DR InParanoid; T1EVT0; -.
DR OMA; HCQHERI; -.
DR OrthoDB; 5472491at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF01344; Kelch_1; 2.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00612; Kelch; 3.
DR SUPFAM; SSF117281; Kelch motif; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 117..218
FT /note="BACK"
FT /evidence="ECO:0000259|SMART:SM00875"
FT COILED 60..88
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 612 AA; 69812 MW; 9B3B74A70A3F6A6F CRC64;
MECCYVSKTL VLVSGTGGRF KVDRDLFHRI SDYYQARVKS GMKDAHHTEL TLDLLSDRCL
AEVEEFMLKM QCNNKEIEEQ SLENLEEAMH GALYLQVGDM IHQYISLLEK HITDSTWIRV
LNIAKKCGAD TLIAKFLDFV CENFTRFVQT SDMLTLSPND LLHLLKSDLL DADSEIDVFK
FVIKWISMEE SRRPLAEKLL AEVRFSLMTT GEKQECSAML SEMNLSHCQH ERIAKARDTT
EVMLIFKGLH GKIDGFHFRP IEHLEASERD TTWRDYPMDD VVVEVTSDKL DRYKAVDLPM
KWCDYEVCIA DRCLYVAGGS EFSFRSILYQ LTSKVYVFSF AQSLWKQCSS MHLPRKSFYF
CSMAEGLFAV SGKTKFNKLT STVERYKPMV DEWQTVTPLP VAVCGPAGCV RKGRMYVSGG
HTSSGDVSDS VWQFDPTCNT WSSVTPLLRA RFNHTMASAG DKLIVVGGAN AVRTFSFDHL
MDGEMYDFEA DQWSDFIKLE KPACSSPSIL IGSSLYLFAG VMDLSGESLV QKINMSKYLN
EKSSDESVVM ERKKTLNENF EKCTAMEEVE EKRTISPDRK DYCEVSSFRF DGGCFRNMCV
TKLPKKLFLQ SL
//
