ID T1FG02_HELRO Unreviewed; 314 AA.
AC T1FG02;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 28-JUN-2023, entry version 36.
DE RecName: Full=Armadillo repeat-containing domain-containing protein {ECO:0000259|Pfam:PF04826};
GN Name=20207751 {ECO:0000313|EnsemblMetazoa:HelroP180520};
GN ORFNames=HELRODRAFT_180520 {ECO:0000313|EMBL:ESN93868.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP180520, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN93868.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP180520}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01007233; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097587; ESN93868.1; -; Genomic_DNA.
DR RefSeq; XP_009028072.1; XM_009029824.1.
DR AlphaFoldDB; T1FG02; -.
DR EnsemblMetazoa; HelroT180520; HelroP180520; HelroG180520.
DR GeneID; 20207751; -.
DR KEGG; hro:HELRODRAFT_180520; -.
DR CTD; 20207751; -.
DR HOGENOM; CLU_886460_0_0_1; -.
DR InParanoid; T1FG02; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR InterPro; IPR006911; ARM-rpt_dom.
DR PANTHER; PTHR15712:SF23; ARM_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15712; ARMADILLO REPEAT CONTAINING PROTEIN; 1.
DR Pfam; PF04826; Arm_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 87..226
FT /note="Armadillo repeat-containing"
FT /evidence="ECO:0000259|Pfam:PF04826"
FT REGION 34..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 36385 MW; 1D7E3AF7D71DF2F0 CRC64;
MHQYAISYKK ILIASVVGVS CFVLYRRFFR RKSKTPTKPS SKESNASEMK NVNSKKNPAK
KNFNIINKYV AVQYLHHLRE VYDRPDSKQL MMLLNTIAEL AAFTENQPTI PTVLRYLELD
VLANHPTKVS LWFLINMSLV DDYHQLFLSK ICTIFSHVWL KNKINCQLEA LKLLINLVNN
EDVVVEFVST PVPDDYVADP LNNRYFEDRD VLLRWLILLN IFMNYVVKDK SVLGPAPEPK
PLTLPSCKLP SSTVSNPSIC HTFGNIYFDE SFRLRLLDSL CLCHKKLSKA NDEEMYQLNL
QLMFMVQELT SILK
//
