ID T1FM73_HELRO Unreviewed; 511 AA.
AC T1FM73;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=Dynein heavy chain tail domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=20209922 {ECO:0000313|EnsemblMetazoa:HelroP184949};
GN ORFNames=HELRODRAFT_184949 {ECO:0000313|EMBL:ESO06705.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP184949, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO06705.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP184949}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01000683; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096324; ESO06705.1; -; Genomic_DNA.
DR RefSeq; XP_009016073.1; XM_009017825.1.
DR AlphaFoldDB; T1FM73; -.
DR STRING; 6412.T1FM73; -.
DR EnsemblMetazoa; HelroT184949; HelroP184949; HelroG184949.
DR GeneID; 20209922; -.
DR KEGG; hro:HELRODRAFT_184949; -.
DR CTD; 20209922; -.
DR eggNOG; ENOG502QTBE; Eukaryota.
DR HOGENOM; CLU_050627_0_0_1; -.
DR InParanoid; T1FM73; -.
DR OMA; RHYCHIN; -.
DR OrthoDB; 3062033at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0034198; P:cellular response to amino acid starvation; IBA:GO_Central.
DR GO; GO:0042149; P:cellular response to glucose starvation; IBA:GO_Central.
DR GO; GO:1904262; P:negative regulation of TORC1 signaling; IBA:GO_Central.
DR GO; GO:0061462; P:protein localization to lysosome; IBA:GO_Central.
DR Gene3D; 1.10.3450.30; -; 1.
DR InterPro; IPR038060; C12orf66-like_central_sf.
DR InterPro; IPR018544; KICS_2.
DR PANTHER; PTHR31581; KICSTOR COMPLEX PROTEIN C12ORF66; 1.
DR PANTHER; PTHR31581:SF1; KICSTOR SUBUNIT 2; 1.
DR Pfam; PF09404; C12orf66_like; 3.
DR SUPFAM; SSF160651; FLJ32549 C-terminal domain-like; 1.
DR SUPFAM; SSF158548; FLJ32549 domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
SQ SEQUENCE 511 AA; 58237 MW; 2B2F00DFC3CD323E CRC64;
MTSTTDLEEE KSFVVDCFLH LSRFSHDKLK ELTLKEKEKE RSKYHANLLW SSFLNLLLTF
NDLEKTFYSL VFLGSANFGA RLLLGKRDDT LNARYRCLLS ELRKIEFAHK GSISPPDPNK
TVSFSGKSQS DPSFCVDADV LKKCTTLEQL AGIVCEQLQH FVLARMNTIS FYEQMPALNN
NKNVSVDDLL KTISTTLEEL LSKVNHPVVE KLRSTYKMEC ETVVNLLKTQ LNLQKCQYLD
SLLSLQSASH NLNTWSNMLT PREARRSTFG SNVQKPASSE LFDWLNRFKN LLLSKFTLYF
FEVLSQQSGS PSEVKTFLAK TFFDFYNRII AFTKRSDACS ILLISSGQLE QVLACKKLGY
NLPCKSIIIP YDADKNVDKV GQNVGIKSPE QPVVVSQVML KSSSAADFHR NNIVLFAYPH
DKSAERHYCH INNMLNTRKQ DLDQQDRIIY AIDVKQQCTS VMTKVEGSIY LVVLLNRKYM
KPDTHITNFC TSLCTDLRCS KHFTGIKSGA K
//
