ID T1FNQ8_HELRO Unreviewed; 641 AA.
AC T1FNQ8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Citrate transporter-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=20210455 {ECO:0000313|EnsemblMetazoa:HelroP186154};
GN ORFNames=HELRODRAFT_186154 {ECO:0000313|EMBL:ESN92181.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP186154, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN92181.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP186154}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family.
CC NADC subfamily. {ECO:0000256|ARBA:ARBA00006772}.
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DR EMBL; AMQM01007726; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097661; ESN92181.1; -; Genomic_DNA.
DR RefSeq; XP_009029687.1; XM_009031439.1.
DR AlphaFoldDB; T1FNQ8; -.
DR EnsemblMetazoa; HelroT186154; HelroP186154; HelroG186154.
DR GeneID; 20210455; -.
DR KEGG; hro:HELRODRAFT_186154; -.
DR CTD; 20210455; -.
DR eggNOG; KOG1281; Eukaryota.
DR HOGENOM; CLU_005170_9_1_1; -.
DR InParanoid; T1FNQ8; -.
DR OMA; YCELAFH; -.
DR OrthoDB; 1359392at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015556; F:C4-dicarboxylate transmembrane transporter activity; IEA:UniProt.
DR GO; GO:0005310; F:dicarboxylic acid transmembrane transporter activity; IEA:UniProt.
DR GO; GO:1901702; F:salt transmembrane transporter activity; IEA:UniProt.
DR CDD; cd01115; SLC13_permease; 1.
DR InterPro; IPR001898; SLC13A/DASS.
DR PANTHER; PTHR10283:SF82; PROTEIN I'M NOT DEAD YET-RELATED; 1.
DR PANTHER; PTHR10283; SOLUTE CARRIER FAMILY 13 MEMBER; 1.
DR Pfam; PF00939; Na_sulph_symp; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 581..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 641 AA; 70369 MW; 2737CE11B0E031E2 CRC64;
MAKDVEIRDS TKPSIWKQIM AIKDTLIIIL TPIILLPLPI VWSAKQGRCA YVILIMIVYW
MTEVIPMAVT ALIPIVLFPW LGVMGSKELC VNYLKDANML FFGGLLVAVA VEKWNLHKRV
ALRVLMLVGS KPKWIIFGFM VVTAFLSMWL NNTATTAMMM PIAHAVLTEL DDNRKKQMIA
RNASKNNLEE KKDANNDHAI EMKEIATDGA ESHLLTVKTD QAAPVVLSKE DEESNKRFAS
FRTALKLCVP YASSIGGCGT LIGCGPNIVL KGQLEVLYSS SSINFTSWLV IGFPAMVVDL
LLAWVFLLII FFGARDTFGL RKQTEEDKDE TANQVIKAEY QKLGSITFAE VVVLVNFLIL
AFLWVSREPE FVPGWGKALN HTTTKTTVKH YYNGSKEITV TEVPASFVTD ASVAITICVL
LFIFPSQWPS YLCFRKKTET RAPGLAPPIL DWPTANKQMP WSVILLLGGG FALADACKGS
KLSDSVGEAL ISLKDLHPFF ISLIMTLVAT VITQFTSNMA TTTIMIPILA QVAAKTCVNP
IYLMLPVTLA SSFAFILPVG TPPNAIAHSY GDITIPQMIK AGLAMCLITN VVLVLSINTW
GYAFFDLGTW PSWAPPCANS TVEVMASVTP MIVNTTTAPV G
//
