ID T1FNZ9_HELRO Unreviewed; 249 AA.
AC T1FNZ9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=14-3-3 domain-containing protein {ECO:0000259|SMART:SM00101};
GN Name=20210546 {ECO:0000313|EnsemblMetazoa:HelroP186472};
GN ORFNames=HELRODRAFT_186472 {ECO:0000313|EMBL:ESN98653.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP186472, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN98653.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP186472}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 14-3-3 family.
CC {ECO:0000256|ARBA:ARBA00006141, ECO:0000256|RuleBase:RU003466}.
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DR EMBL; AMQM01001027; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097143; ESN98653.1; -; Genomic_DNA.
DR RefSeq; XP_009022653.1; XM_009024405.1.
DR AlphaFoldDB; T1FNZ9; -.
DR STRING; 6412.T1FNZ9; -.
DR EnsemblMetazoa; HelroT186472; HelroP186472; HelroG186472.
DR GeneID; 20210546; -.
DR KEGG; hro:HELRODRAFT_186472; -.
DR CTD; 20210546; -.
DR eggNOG; KOG0841; Eukaryota.
DR HOGENOM; CLU_058290_1_0_1; -.
DR InParanoid; T1FNZ9; -.
DR OMA; PLCNEER; -.
DR OrthoDB; 920089at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR Gene3D; 1.20.190.20; 14-3-3 domain; 1.
DR InterPro; IPR000308; 14-3-3.
DR InterPro; IPR023409; 14-3-3_CS.
DR InterPro; IPR036815; 14-3-3_dom_sf.
DR InterPro; IPR023410; 14-3-3_domain.
DR PANTHER; PTHR18860; 14-3-3 PROTEIN; 1.
DR PANTHER; PTHR18860:SF160; 14-3-3 PROTEIN ZETA; 1.
DR Pfam; PF00244; 14-3-3; 1.
DR PIRSF; PIRSF000868; 14-3-3; 1.
DR PRINTS; PR00305; 1433ZETA.
DR SMART; SM00101; 14_3_3; 1.
DR SUPFAM; SSF48445; 14-3-3 protein; 1.
DR PROSITE; PS00796; 1433_1; 1.
DR PROSITE; PS00797; 1433_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 5..244
FT /note="14-3-3"
FT /evidence="ECO:0000259|SMART:SM00101"
FT COILED 74..105
FT /evidence="ECO:0000256|SAM:Coils"
FT SITE 58
FT /note="Interaction with phosphoserine on interacting
FT protein"
FT /evidence="ECO:0000256|PIRSR:PIRSR000868-1"
FT SITE 129
FT /note="Interaction with phosphoserine on interacting
FT protein"
FT /evidence="ECO:0000256|PIRSR:PIRSR000868-1"
SQ SEQUENCE 249 AA; 28368 MW; 4178DC3538F8972B CRC64;
MAAERDELVQ KAKLAEQAER YEDMAVDMKK VTELGTELSN EERNLLSVAY KNVVGARRSS
WRVISSIEQK TEGNEKKLNM VKEYKEKVEK ELKNVCREVL DLLDKFLIAK AANAESKVFY
LKMKGDYYRY LAEVSVNEER SSVVTESQNA YQAALDIAKE QMQPTHPIRL GLALNYSVFF
YEILNSQDRA CHLAKLAFDE AIAELDTLNE DSYKDSTLIM QLLRDNLTLW TSDAQGDAVE
GEETQGVAE
//
