ID T1FPL7_HELRO Unreviewed; 731 AA.
AC T1FPL7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESO13036.1, ECO:0000313|EnsemblMetazoa:HelroP188076};
GN Name=20210764 {ECO:0000313|EnsemblMetazoa:HelroP188076};
GN ORFNames=HELRODRAFT_188076 {ECO:0000313|EMBL:ESO13036.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP188076, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO13036.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP188076}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01000288; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB095811; ESO13036.1; -; Genomic_DNA.
DR RefSeq; XP_009009756.1; XM_009011508.1.
DR AlphaFoldDB; T1FPL7; -.
DR STRING; 6412.T1FPL7; -.
DR EnsemblMetazoa; HelroT188076; HelroP188076; HelroG188076.
DR GeneID; 20210764; -.
DR KEGG; hro:HELRODRAFT_188076; -.
DR CTD; 20210764; -.
DR eggNOG; KOG0800; Eukaryota.
DR HOGENOM; CLU_379125_0_0_1; -.
DR InParanoid; T1FPL7; -.
DR OrthoDB; 140984at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16494; RING-CH-C4HC3_ZSWM2; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR007527; Znf_SWIM.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR InterPro; IPR039903; Zswim2.
DR PANTHER; PTHR21540:SF0; E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2; 1.
DR PANTHER; PTHR21540; RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS50966; ZF_SWIM; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 47..81
FT /note="SWIM-type"
FT /evidence="ECO:0000259|PROSITE:PS50966"
FT DOMAIN 142..191
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 222..284
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT REGION 531..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 707..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 731 AA; 83478 MW; ECB53D11D40D265E CRC64;
MAPLWRRVCP DLVVVRQQEA ADATIYILRD IGPTGFLLKE ENDQKVQKVL IGERHTCSCT
NFMKNSSELC KHLCWILLKK FKLSPSDPVS WQLGLCERDV NMLLKNAKSK SRTSKDLKTE
TFKSEIKPKL IEQREITDED SCPICQEDLL GSPQKITFCR YGCGNSVHVK CMRVWAAHRK
VDSTVECPFC RTDFGPITLL NESKYRLFGP RLTNYQNHMM EHSRTYCHSC GASPIIGKCY
KCDFCDTDFF LCQPCFKTEI HGEHQFVYRA KMNQRWQPVC NRDFIIKLRS LHLNDILTRD
IVDADYDTLL LQLSTGTYNS NTAANDLQEC HLISFPTRRL KTNDPLLSQS NNNKGGCLCK
ICNIVLKEGH EVRMVPCCKT WFHRECIDAC SSSDNSSKSN ARTERAKKCK LFGGGDDASS
IKIRGLNIKK TFSDDFGGGD DDEENGDTIF ENLYPYASRY NRYKEKCNIS LKSRHASLDS
TAQNQAPLNF KLQNRMTTAK RHFLPKLIRD NQNTLSNKNL LIKSAHSSSA KSSSSLLLEP
TPVRGKSDDI NSDNVIDNNN NNNSNINNLN KYVKLNAIKR EHSWPTMDKS KIAYINNNNN
SNDRIIRKND VNERSETSNQ LNIQRDVFPK VSTATNVSQK TKLHNNNPTL NKHYTYAIHT
NTPVLYEEDD ENKVEIANDN NNDNLIVCKT QSAVIDYEAS DDDYNECGSH DLNHNTKTSR
DEKLTYKDSS C
//
