ID T1FRK6_HELRO Unreviewed; 419 AA.
AC T1FRK6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 28-JUN-2023, entry version 37.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN Name=20211453 {ECO:0000313|EnsemblMetazoa:HelroP189995};
GN ORFNames=HELRODRAFT_189995 {ECO:0000313|EMBL:ESO11540.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP189995, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO11540.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP189995}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01002446; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB095812; ESO11540.1; -; Genomic_DNA.
DR RefSeq; XP_009010028.1; XM_009011780.1.
DR AlphaFoldDB; T1FRK6; -.
DR EnsemblMetazoa; HelroT189995; HelroP189995; HelroG189995.
DR GeneID; 20211453; -.
DR KEGG; hro:HELRODRAFT_189995; -.
DR CTD; 20211453; -.
DR HOGENOM; CLU_664446_0_0_1; -.
DR InParanoid; T1FRK6; -.
DR OrthoDB; 5383069at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SUPFAM; SSF101908; Putative isomerase YbhE; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 8..48
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 419 AA; 48596 MW; 644A79B6FA655E8F CRC64;
MERSILICEV CGRIMKPPTA MLPCKHTYCK TCIDEVTNKR GGVKCWDCGE QYRSKRHFRR
NLFLEQLLTL KAIEEEIILM QADVERFPKF LENAKMPRMV TAIHYSSSSG LLYIAFHDNV
FFISVVRCHF VDENVLRLNN QELLPAAAIR THVSQNICDM TGYENRIFFS DDNRPKITQY
KFKESFATAT KVSKFNLILG PGSKHGDYFV SSVFIGFSGT RLSLTNDFLN ETCLLVTTNT
PTLLIVGTKN RLVLLKKILL PDGSPKHALF LNSKTLAVAG RTQNSYLTFF NFNFDSARRN
ITLQKKQFVF RKELYRFYSC LWEPCYLAHN RLNKTLFITN KGSETVKLFG VNLDSDDVVV
IEDCQKLSNL VKRYDAVEYR SPLLDQYMPF EPTKITYAEN VKYLFEINKV QSRIFWYNI
//
