ID T1FTM9_HELRO Unreviewed; 429 AA.
AC T1FTM9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=SAP domain-containing protein {ECO:0000259|PROSITE:PS50800};
GN Name=20212176 {ECO:0000313|EnsemblMetazoa:HelroP192152};
GN ORFNames=HELRODRAFT_192152 {ECO:0000313|EMBL:ESO02803.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP192152, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO02803.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP192152}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01004849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096716; ESO02803.1; -; Genomic_DNA.
DR RefSeq; XP_009019017.1; XM_009020769.1.
DR AlphaFoldDB; T1FTM9; -.
DR EnsemblMetazoa; HelroT192152; HelroP192152; HelroG192152.
DR GeneID; 20212176; -.
DR KEGG; hro:HELRODRAFT_192152; -.
DR CTD; 20212176; -.
DR eggNOG; ENOG502SERV; Eukaryota.
DR HOGENOM; CLU_639806_0_0_1; -.
DR InParanoid; T1FTM9; -.
DR OrthoDB; 2917167at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR008906; HATC_C_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR46169; DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A; 1.
DR PANTHER; PTHR46169:SF15; DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A; 1.
DR Pfam; PF05699; Dimer_Tnp_hAT; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 4..38
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
SQ SEQUENCE 429 AA; 48612 MW; 3C2DF3A44036FE2F CRC64;
MSKLCGLNVV QLREELQKRS LVTSGNKEVL VARLREALIE EDLKIVASRN MFVENLLTSR
SLTTTHFVSD TKQSTDFFWF RDSGIRVNLG VQNVQKASGR RQESYVWEYF QYDPVTDRST
CLCEISSTSS SQSTSASRVC GKTLKGKNAT NLKTHLEYFH SDAFNKVKDK EKVKNKLSNK
ICNASGSDQK TQPKIATFVD KINAYNENSK VYKDKLDAVV DLFAKTSLPL SLLDCPVFQQ
FVNTMDSQFK LPVLDLVPAA ATLLDLRYNW TLLMSVNSAL LSMAKKYIVQ KINVNCKDSN
QLQIDQDLQQ RPAKRFKLMT SLVLPTCSQS RTDKLLSVYS DVEEEIDRYI SKINSQLLPE
DEDSIVAWSK KTDLPLLSGI APNILALPCS QAFVERLFST CSILTEGRRN KLSNNLEKRL
FLKHNLQLV
//
