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Database: UniProt
Entry: T1FVZ3_HELRO
LinkDB: T1FVZ3_HELRO
Original site: T1FVZ3_HELRO 
ID   T1FVZ3_HELRO            Unreviewed;       636 AA.
AC   T1FVZ3;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   16-JAN-2019, entry version 30.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESN92216.1, ECO:0000313|EnsemblMetazoa:HelroP194357};
GN   Name=20212989 {ECO:0000313|EnsemblMetazoa:HelroP194357};
GN   ORFNames=HELRODRAFT_194357 {ECO:0000313|EMBL:ESN92216.1};
OS   Helobdella robusta (Californian leech).
OC   Eukaryota; Metazoa; Lophotrochozoa; Annelida; Clitellata; Hirudinea;
OC   Hirudinida; Glossiphoniiformes; Glossiphoniidae; Helobdella.
OX   NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP194357, ECO:0000313|Proteomes:UP000015101};
RN   [1] {ECO:0000313|EnsemblMetazoa:HelroP194357, ECO:0000313|Proteomes:UP000015101}
RP   NUCLEOTIDE SEQUENCE.
RA   Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA   Otillar R.P., Terry A.Y., Boore J.L., Simakov O., Marletaz F.,
RA   Cho S.-J., Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T.,
RA   Lv J., Arendt D., Savage R., Osoegawa K., de Jong P., Lindberg D.R.,
RA   Seaver E.C., Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ESN92216.1, ECO:0000313|EnsemblMetazoa:HelroP194357, ECO:0000313|Proteomes:UP000015101}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H.,
RA   Aerts A., Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V.,
RA   Lindberg D.R., Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
RN   [3] {ECO:0000313|EnsemblMetazoa:HelroP194357}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; AMQM01007757; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMQM01007758; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KB097661; ESN92216.1; -; Genomic_DNA.
DR   RefSeq; XP_009029717.1; XM_009031469.1.
DR   EnsemblMetazoa; HelroT194357; HelroP194357; HelroG194357.
DR   GeneID; 20212989; -.
DR   KEGG; hro:HELRODRAFT_194357; -.
DR   CTD; 20212989; -.
DR   OMA; FANDACE; -.
DR   OrthoDB; 94996at2759; -.
DR   Proteomes; UP000015101; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000015101};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN      117    171       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      178    228       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      236    292       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      299    365       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      370    426       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED       91    114       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   636 AA;  71684 MW;  79C099FB61A9076E CRC64;
     MAESSSYILH MGDIISLYAE GNVSGFISTL GLVDDRCVVQ PETGDLNNPP KKFRDCLFKV
     CPNNRYSAQK QFWKATKQNN NANLTNVNTD LSLLKKLSNA AEQEKKQNEL EYKKSLGMPI
     TYGNSIQLLH LKSNKFITVN KRLPAQMEKN AMRVTLDAAG NEGSWLTILP FYKLRSPGDK
     VMVGDKVILS SVNSTQPLHA SNLDLPDNPG CKEVNSVNSN TCWKVNLFMD FHENIETVLK
     GGDVVRLFHA EQEKFLTGDE YKKKHYVFLR TTGRTSATAA TSSNALWEVE VVHDDPCRGG
     AGHWNSLFRF KHLASGHYLA AEVDNDPNSD PMRTKLRGNP QAPVYCLVSV PHGHDMASIF
     ELDPTTMTSD STVPRSSFVR LRHYLTKAWI HSISLPIDKD EDKPIMSKVG CASIKEDKEA
     FAIVPVSPQE VRDLDFANDA GKVLANIAKK LEKGPMSVTQ LMRDLIYFVA YQEYSTLDPL
     DIVMVHSDRE RSKLLREQNV LKQLFKILKA PFTDFGQGPQ MKMEDLADPK QAHFKYICQL
     SYHILKLSQH DYRKNQEYIA KEFPFMQKQI GYDVYAEDTM TALLHNNRQL LEKHITASEI
     ETFVNLISGL PIGPVCIESR GNPSNPGAHL QIRTGR
//
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