ID T1FX01_HELRO Unreviewed; 123 AA.
AC T1FX01;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=IRF tryptophan pentad repeat domain-containing protein {ECO:0000259|PROSITE:PS51507};
GN Name=20213349 {ECO:0000313|EnsemblMetazoa:HelroP62390};
GN ORFNames=HELRODRAFT_62390 {ECO:0000313|EMBL:ESO13131.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP62390, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO13131.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP62390}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01000335; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMQM01000336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB095811; ESO13131.1; -; Genomic_DNA.
DR RefSeq; XP_009009851.1; XM_009011603.1.
DR AlphaFoldDB; T1FX01; -.
DR STRING; 6412.T1FX01; -.
DR EnsemblMetazoa; HelroT62390; HelroP62390; HelroG62390.
DR GeneID; 20213349; -.
DR KEGG; hro:HELRODRAFT_62390; -.
DR CTD; 20213349; -.
DR eggNOG; ENOG502QUE4; Eukaryota.
DR HOGENOM; CLU_056386_3_1_1; -.
DR InParanoid; T1FX01; -.
DR OMA; FLEWARN; -.
DR OrthoDB; 3740806at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF17; IRF TRYPTOPHAN PENTAD REPEAT DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00605; IRF; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 1..108
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
SQ SEQUENCE 123 AA; 14670 MW; BFD1B597D02DE463 CRC64;
RVLLRPWLEN LIESQVVHGL EWLDQKQLIF KIPWKHRSKK SWSVEHSSVF LEWARNTGRW
TPGDPEPNYA QLKTRLRCAF NKAPDILEIK EMHKTKCEEA YKVYRFIPKE SQCSLIIIIS
PKL
//
