ID T1FYV5_HELRO Unreviewed; 379 AA.
AC T1FYV5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=UDENN domain-containing protein {ECO:0000259|PROSITE:PS50211};
GN Name=20214003 {ECO:0000313|EnsemblMetazoa:HelroP67031};
GN ORFNames=HELRODRAFT_67031 {ECO:0000313|EMBL:ESN99237.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP67031, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN99237.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP67031}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01001158; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097143; ESN99237.1; -; Genomic_DNA.
DR RefSeq; XP_009022517.1; XM_009024269.1.
DR AlphaFoldDB; T1FYV5; -.
DR STRING; 6412.T1FYV5; -.
DR EnsemblMetazoa; HelroT67031; HelroP67031; HelroG67031.
DR GeneID; 20214003; -.
DR KEGG; hro:HELRODRAFT_67031; -.
DR CTD; 20214003; -.
DR eggNOG; KOG3569; Eukaryota.
DR HOGENOM; CLU_008196_3_0_1; -.
DR InParanoid; T1FYV5; -.
DR OMA; PTIPESX; -.
DR OrthoDB; 5398783at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR Gene3D; 3.30.450.200; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 6.10.140.1000; -; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR040032; DENND1A/B/C.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR13196; DENN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR13196:SF14; UDENN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR PROSITE; PS50211; DENN; 1.
PE 4: Predicted;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 1..341
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
SQ SEQUENCE 379 AA; 44043 MW; 9FB194AEDAD4A1D8 CRC64;
ELLKSIKKFV FPFDPSFKSP IVDHFTFVLT DIDGKFKFGF CRLSEGSKLC HCVVSCHPWF
EIFYRLLNQF SDLMNSHQVS YINKWIDSLL RINYLNSTEP ASNRELTSSS VFVFQVPDAT
KLMSIPQSRN LTEYYCAVDS KNMMQIFASM LLERRIIVTS HKLSKLTACI HTAAHLLFPF
HWQHIFIPIL PPHLLDFCSA PMPFLIGIHT SLWNRINKDD LSDALVLDAD ANDILSEFND
LDHFPPDVLA KLKKYLNVKT KMKNLDGEII PRAFLKVLVI IFGGYRTAFK MNEDKEIVFD
SGLFLQSRPK HMKNFLQVVL QSQIFQQFIE ERLNLIKAKK GYNDAFEAEI STYDSKRVKR
KVCMHCVHTI HIIHSQIYH
//
