ID T1G0R8_HELRO Unreviewed; 506 AA.
AC T1G0R8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Phospholipid/glycerol acyltransferase domain-containing protein {ECO:0000259|SMART:SM00563};
GN Name=20214666 {ECO:0000313|EnsemblMetazoa:HelroP71793};
GN ORFNames=HELRODRAFT_71793 {ECO:0000313|EMBL:ESO11661.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP71793, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO11661.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP71793}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GPAT/DAPAT family.
CC {ECO:0000256|ARBA:ARBA00007937}.
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DR EMBL; AMQM01002511; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB095812; ESO11661.1; -; Genomic_DNA.
DR RefSeq; XP_009010149.1; XM_009011901.1.
DR AlphaFoldDB; T1G0R8; -.
DR STRING; 6412.T1G0R8; -.
DR EnsemblMetazoa; HelroT71793; HelroP71793; HelroG71793.
DR GeneID; 20214666; -.
DR KEGG; hro:HELRODRAFT_71793; -.
DR CTD; 20214666; -.
DR eggNOG; KOG3730; Eukaryota.
DR HOGENOM; CLU_017332_0_0_1; -.
DR InParanoid; T1G0R8; -.
DR OMA; VIAAGMX; -.
DR OrthoDB; 5478811at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0031966; C:mitochondrial membrane; IBA:GO_Central.
DR GO; GO:0005778; C:peroxisomal membrane; IBA:GO_Central.
DR GO; GO:0004366; F:glycerol-3-phosphate O-acyltransferase activity; IBA:GO_Central.
DR GO; GO:0016287; F:glycerone-phosphate O-acyltransferase activity; IBA:GO_Central.
DR GO; GO:0008611; P:ether lipid biosynthetic process; IBA:GO_Central.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IBA:GO_Central.
DR GO; GO:0019432; P:triglyceride biosynthetic process; IBA:GO_Central.
DR CDD; cd07993; LPLAT_DHAPAT-like; 1.
DR InterPro; IPR022284; GPAT/DHAPAT.
DR InterPro; IPR045520; GPAT/DHAPAT_C.
DR InterPro; IPR041728; GPAT/DHAPAT_LPLAT.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR12563:SF17; DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE; 1.
DR PANTHER; PTHR12563; GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR Pfam; PF19277; GPAT_C; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 126..255
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 506 AA; 57946 MW; E23C041D0C76A89F CRC64;
KDGYRDILQE RRGDLDLGFT FKSFHNVPTY KYHSPRNYSK LKTDVLSSDR LKYTIERLSG
EDKVKEALLR KEAELMYTDM AHLLNLKGVR TMAFMAIKVF KALFRRVYVN EEGVNRLQHI
MQEYPVVLMP THRSYMDFVL VTFVCYHYNL PVPAVAAAMD FKGMKLMGWL LQNCGAFYIR
RSFGSDHLYW AIFTEYVQTQ LKNGDHPLEF FIEGTRSRTN KSYIPKIGML AASLESYFKA
ELPDVMIVPV SLTFDRIVEE SLYAFELLGI PKPRESTSGL LKARKILSED FGSVHIHIGE
AISIRQVSDG KIDRVSHALE PRYINSLSGD EQILITNLAY QIVKQQQRQF IIPPGTLLAT
VFIQHAARGL HINELSKKVD WLKRQACNLG AYVDWPGNVS LMNVIHMCLR LHKNILKLNE
QDVSSSSQSS SSSPSHPLNS SSLLLDASNY LMLASYRNHV THLFVDVAMV MMAIKSRSKH
CRELSLGAIL FLKFFFSSFH CNMKTT
//
