ID T1G2N0_HELRO Unreviewed; 517 AA.
AC T1G2N0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=ABC1 atypical kinase-like domain-containing protein {ECO:0000259|Pfam:PF03109};
GN Name=20215328 {ECO:0000313|EnsemblMetazoa:HelroP76709};
GN ORFNames=HELRODRAFT_76709 {ECO:0000313|EMBL:ESO07220.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP76709, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO07220.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP76709}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. ADCK protein
CC kinase family. {ECO:0000256|ARBA:ARBA00009670}.
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DR EMBL; AMQM01003586; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096222; ESO07220.1; -; Genomic_DNA.
DR RefSeq; XP_009014598.1; XM_009016350.1.
DR AlphaFoldDB; T1G2N0; -.
DR STRING; 6412.T1G2N0; -.
DR EnsemblMetazoa; HelroT76709; HelroP76709; HelroG76709.
DR GeneID; 20215328; -.
DR KEGG; hro:HELRODRAFT_76709; -.
DR CTD; 20215328; -.
DR eggNOG; KOG1235; Eukaryota.
DR HOGENOM; CLU_006533_2_6_1; -.
DR InParanoid; T1G2N0; -.
DR OMA; DVMTTMV; -.
DR OrthoDB; 177137at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd13969; ADCK1-like; 1.
DR InterPro; IPR004147; ABC1_dom.
DR InterPro; IPR045307; ADCK1_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR43173:SF43; AARF DOMAIN-CONTAINING KINASE 5; 1.
DR PANTHER; PTHR43173; ABC1 FAMILY PROTEIN; 1.
DR Pfam; PF03109; ABC1; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 101..344
FT /note="ABC1 atypical kinase-like"
FT /evidence="ECO:0000259|Pfam:PF03109"
SQ SEQUENCE 517 AA; 61002 MW; B67DB33F6C65FAFC CRC64;
YHTLDGKRKR KFTLLLSGFT RFLRSVYIGT LISIDYKLSL WGIQENSREW NKMIPAVHKR
SAERVLQGCL RNSGLYIKLG QGLVCLNHIL PKEYIDTLEV LQDQALARKK NEVEALFLED
FGMKPMEMFK EFDDVPIAAA SLAQVHRAVT HDDKKVAVKV QYIDLQDRFV GDIRTVELLL
KVIEWMHPNF GFAWVLQDLK GTLAKELDFE NEGRNGERCR QDLKHFKFIY VPKVYWMYTS
KRVLTCEYID GCKVNDLDRI KQMDITVAEV NEKLVKCFSH QLFHTGFVHA DPHPGNVFVR
KDKQNRCQLV LLDHGLYEFL SINDRKYLCR FYEAIMTRND RQMEFYSRKL GVKDYKIFSE
ILVQRPISIS SIKLSSVMTP ADLEYMRVMA QKHFDKIMAV LRDMPRPMLL VIRNLNTIRA
ISKQLHHPVD RYSIMARWFV HLSISIYLFL YKNSNKLFFK PINSAISGSY NNRYTTSKRR
KIVNTLKYFY HIFVFEFKLR FNTMRLFDGE VFGPVLQ
//
