ID T1G2T2_HELRO Unreviewed; 859 AA.
AC T1G2T2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=UDENN domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=20215380 {ECO:0000313|EnsemblMetazoa:HelroP77102};
GN ORFNames=HELRODRAFT_77102 {ECO:0000313|EMBL:ESO07026.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP77102, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO07026.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP77102}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01003769; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096275; ESO07026.1; -; Genomic_DNA.
DR RefSeq; XP_009015122.1; XM_009016874.1.
DR AlphaFoldDB; T1G2T2; -.
DR STRING; 6412.T1G2T2; -.
DR EnsemblMetazoa; HelroT77102; HelroP77102; HelroG77102.
DR GeneID; 20215380; -.
DR KEGG; hro:HELRODRAFT_77102; -.
DR CTD; 20215380; -.
DR eggNOG; KOG2127; Eukaryota.
DR HOGENOM; CLU_003074_3_0_1; -.
DR InParanoid; T1G2T2; -.
DR OMA; YNNISIC; -.
DR OrthoDB; 1079051at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0031410; C:cytoplasmic vesicle; IBA:GO_Central.
DR GO; GO:0032483; P:regulation of Rab protein signal transduction; IBA:GO_Central.
DR Gene3D; 2.100.10.50; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR023341; MABP.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR12296; DENN DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR12296:SF30; DENN DOMAIN-CONTAINING PROTEIN CRAG; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00800; uDENN; 1.
DR PROSITE; PS50211; DENN; 1.
DR PROSITE; PS51498; MABP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 33..191
FT /note="MABP"
FT /evidence="ECO:0000259|PROSITE:PS51498"
FT DOMAIN 183..635
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
SQ SEQUENCE 859 AA; 97095 MW; 645C7F85F4EDE5CB CRC64;
MAETPKIVNY FFVTGLPEKT IEKEPITRYT KPKLPITDIV VINRTQGEAT PKGFECLELT
PTNFPANLNH GSLVSPEMYI CVKRGRDSPP VIDIGVYYQS SKKQLRPGVE MITSTPYGRS
ANVNNTVGEK IYITFCRAIE LVDWDTLAVC DICIILPSKG EAVPHAFRQI NKPLNLGMIG
SDVYLCYRKS YIKNKCLTYD AGELLFRYPT TDDPNFPLPQ QLPMFCLPQG AAIERWGANS
RYPLPVYSTF VLTDQSGLKC YGAAVVFYKD FNSKYFTQKQ REFFGDEKKN TSSVHTKHKQ
TNKQQSICLL SRWPFFDSFK KFLLYLYRIS VSGPQGIPIE RYISHFIDEI PFPSPERPYI
SIHLSTEEIT IMLPDESPLT KSGASYSKFL LNLGPENCIS ILLYVLMEHK IVIHSLRPDL
LTCVAETAST MIFPFQWQCP YVPLCPLQLS DVVDSPTPFI IGLDSSYFDS NNQPPDDITY
VDLDAQSISL SKERSSDTLK LLPKKPLRRL RTSLEQLYDG LINDPSCPST PSELDSHGGF
NIRDALNQQN QRKMDAQIQE CFLLFMADIM KGYSSYLRPV SNYSPGDVIN ISGLFDVQGF
LKSHDKSYGK LLSQLIRTQY FCRFLEERSL GSCENVSLTF FDACLDKLKS DPNAALIEVE
EMFLSERTAV ISFLDNVQEI PNVSYSYNSF SDLDLKLFSM TLHNVKYQKT TKTIKNDSLF
PFTASAATPS SLLPTTANTS PSLSSSSQFM TSSSTSTSSA ARCLLWVTYS IWFTLLPAFI
RTSTAKKLLL SIAHKSMVDF LKRGGRPLDE VLPYKIFFQL CGIYNEPRYA NDVYNQMISC
NIRLDVATYG YYNSVSGVV
//
